2-Chloro-ethanesulfonic acid; compound with trimethyl-amine

Base Information

• Chemical Name: 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine
• CAS No.: 19030-99-0
• Molecular Formula: C₂H₅ClO₃S*C₃H₉N
• Molecular Weight: 203.69
• Mol file: 19030-99-0.mol

Synonyms:

Chemical Property of 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine

There total 3 articles about 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

2-hydroxyethane-1-sulfonyl chloride (78303-70-5) + butan-1-ol (71-36-3) → 2-(N,N,N-trimethylamino)ethanesulfonate (7465-57-8) + butyl 2-hydroxyethanesulfonate (78303-74-9) + 2-Hydroxy-ethanesulfonic acid; compound with trimethyl-amine (78303-75-0) + 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine (19030-99-0)

Guidance literature:

With trimethylamine;

DOI:10.1039/c39810000295

Reference yield: 30.0%

2-hydroxyethane-1-sulfonyl chloride (78303-70-5) + trimethylamine (75-50-3) → 2-(N,N,N-trimethylamino)ethanesulfonate (7465-57-8) + butyl 2-hydroxyethanesulfonate (78303-74-9) + 2-Hydroxy-ethanesulfonic acid; compound with trimethyl-amine (78303-75-0) + 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine (19030-99-0)

Guidance literature:

In butan-1-ol;

DOI:10.1039/c39810000295

Reference yield:

butan-1-[2H]ol (4712-38-3) + 2-hydroxyethane-1-sulfonyl chloride (78303-70-5) → 2-(N,N,N-trimethylamino)ethanesulfonate (7465-57-8) + butyl 2-hydroxyethanesulfonate (78303-74-9) + C6H13(2)HO4S (78303-73-8) + 2-Chloro-ethanesulfonic acid; compound with trimethyl-amine (19030-99-0)

Guidance literature:

With trimethylamine; In dichloromethane; Yield given. Further byproducts given; Ambient temperature;

upstream raw materials:

butan-1-[2H]ol

2-hydroxyethane-1-sulfonyl chloride

trimethylamine

butan-1-ol

Refernces

• 1、 King, James Frederick,Hillhouse, John Henry. "Organic sulfur mechanisms. 24. Preparation and reaction of 2-hydroxyethanesulfonyl chloride, the first hydroxyalkanesulfonyl chloride". . p. 1583 - 1593. Retrieved 2007/10/02.