1-(1,2-diphenylethyl)piperidine hydrochloride

Base Information

• Chemical Name: 1-(1,2-diphenylethyl)piperidine hydrochloride
• CAS No.: 28383-15-5
• Molecular Formula: C19H23 N . Cl H
• Molecular Weight: 0
• Hs Code.: 2933399090
• Mol file: 28383-15-5.mol

Synonyms:Piperidine,1-(1,2-diphenylethyl)-, hydrochloride, (?à)- (8CI); Piperidine, 1-(1,2-diphenylethyl)-, hydrochloride;dl-1,2-Diphenyl-1-piperidinoethane hydrochloride

Chemical Property of 1-(1,2-diphenylethyl)piperidine hydrochloride

Chemical Property:

• Vapor Pressure: 4.14E-05mmHg at 25°C
• Boiling Point: 351.3°Cat760mmHg
• Flash Point: 150.3°C
• PSA: 3.24000
• Density: g/cm³
• LogP: 5.19620

Purity/Quality:

99% ^*data from raw suppliers

Diphenidine (hydrochloride) ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Diphenidine is a homeomorph of the NMDA receptor channel blocker, MK 801, that has been identified as a designer drug. The (S)- and (R)- enantiomers of diphenidine have been reported to inhibit MK 801 binding to NMDA receptors in rat brain membranes with Ki values of 0.13 and 5.25 μM, respectively. It has been studied as a neuroprotective agent for the treatment of brain injury following hypoxia. This product is intended for forensic and research applications.[Cayman Chemical]

Technology Process of 1-(1,2-diphenylethyl)piperidine hydrochloride

There total 1 articles about 1-(1,2-diphenylethyl)piperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(±)-1-(1,2-diphenylethyl)piperidine (36794-52-2) → (+/-)-1-(1,2-diphenylethyl)piperidine hydrochloride (28383-15-5)

Guidance literature:

With hydrogenchloride; water; at 4 - 40 ℃;

DOI:10.1016/j.bmc.2009.03.025

upstream raw materials:

(±)-1-(1,2-diphenylethyl)piperidine

Refernces