IMiquiMod (Maleate)

Base Information

• Chemical Name: IMiquiMod (Maleate)
• CAS No.: 896106-16-4
• Molecular Formula: C₄H₄O₄*C₁₄H₁₆N₄
• Molecular Weight: 356.381
• Mol file: 896106-16-4.mol

Synonyms:

Chemical Property of IMiquiMod (Maleate)

Chemical Property:

Purity/Quality:

>98% ^*data from raw suppliers

ImiquimodMaleate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of IMiquiMod (Maleate)

There total 3 articles about IMiquiMod (Maleate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

imiqimod (99011-02-6) → 4-amino-1-isobutyl-1H-imidazo-[4,5-c]-quinoline maleate (896106-16-4)

Guidance literature:

With maleic acid; In methanol; water; at 74 ℃; for 0.5h;

Reference yield: 91.0%

maleic acid (110-16-7,26099-09-2) + imiqimod (99011-02-6) → 4-amino-1-isobutyl-1H-imidazo-[4,5-c]-quinoline maleate (896106-16-4)

Guidance literature:

In methanol; water; at 74 ℃; Heating / reflux;

Reference yield: 89.0%

(2E)-but-2-enedioic acid (110-17-8,26099-09-2) + imiqimod (99011-02-6) → 4-amino-1-isobutyl-1H-imidazo-[4,5-c]-quinoline fumarate (896106-16-4)

Guidance literature:

In water; N,N-dimethyl-formamide; at 160 ℃; for 0.5h;

upstream raw materials:

maleic acid

imiqimod

(2E)-but-2-enedioic acid

Refernces

• 1、 -. "A PROCESS FOR PREPARATION OF 4-AMINO-1-ISOBUTYL-1H-IMIDAZO[4,5-C]-QUINOLINE (IMIQUIMOD)". Page/Page column 11. . Retrieved 2008/06/13.