PMA HYDROCHLORIDE

Base Information

• Chemical Name: PMA HYDROCHLORIDE
• CAS No.: 52740-56-4
• Molecular Formula: C₁₀H₁₅NO*(x)ClH
• Molecular Weight: 201.69
• Mol file: 52740-56-4.mol

Synonyms:

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of PMA HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0139mmHg at 25°C
• Flash Point: 11?°C
• Storage Temp.: 2-8°C

Purity/Quality:

Safty Information:

• Hazard Codes: Xn,T,F
• Statements: 22-39/23/24/25-23/24/25-11
• Safety Statements: 36/37/39-45-36/37-16-7

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PMA HYDROCHLORIDE

There total 11 articles about PMA HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-methoxybenzyl methyl ketone (122-84-9) → 4-methoxyamphetamine (50505-81-2,52740-56-4)

Guidance literature:

4-methoxybenzyl methyl ketone; With ammonium hydroxide; hydrogen; at 50 ℃; for 20h; under 7500.75 Torr; Autoclave;

With hydrogenchloride; In diethyl ether;

DOI:10.1002/cssc.202100553

Reference yield: 89.0%

C15H21NO6S → l-para-Methoxyamphetamine hydrochloride (50505-80-1,50505-81-2,52740-56-4)

Guidance literature:

C₁₅H₂₁NO₆S; With sodium tetrahydroborate; lithium chloride; In diethylene glycol dimethyl ether; at 80 ℃; for 24h;

With hydrogenchloride; In ethyl acetate; at 30 ℃; for 12h;

Reference yield: 86.0%

N-Cbz-2-(4-methoxyphenyl)-1-methylethylamine (115424-09-4) → l-para-Methoxyamphetamine hydrochloride (50505-80-1,50505-81-2,52740-56-4)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 3h; Ambient temperature;

DOI:10.1080/00397919808007167

upstream raw materials:

[(S)-2-(4-Methoxy-phenyl)-1-methyl-ethyl]-carbamic acid benzyl ester

4-methoxybenzyl methyl ketone

N-Cbz-2-(4-methoxyphenyl)-1-methylethylamine

L-tyrosine ethyl ester

Refernces

• 1、 Elfinger, Matthias,Sch?nauer, Timon,Thom?, Sabrina L. J.,St?glich, Robert,Drechsler, Markus,Zobel, Mirijam,Senker, Jürgen,Kempe, Rhett. "Co-Catalyzed Synthesis of Primary Amines via Reductive Amination employing Hydrogen under very mild Conditions". . p. 2360 - 2366. Retrieved 2021/05/03.
• 2、 -. "PROCESS FOR PREPARING ISOMERS OF CARMOTEROL". Page/Page column 49-50. . Retrieved 2008/12/07.