Technology Process of 2-morpholino-8-(naphthalen-1-yl)-4H-1,3-benzoxazin-4-one
There total 6 articles about 2-morpholino-8-(naphthalen-1-yl)-4H-1,3-benzoxazin-4-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate;
In
1,4-dioxane; water;
at 50 ℃;
for 16h;
Schlenk technique;
Inert atmosphere;
DOI:10.1016/j.ejmech.2016.01.042
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: dichloromethane
2.1: sodium hydrogencarbonate / isopropyl alcohol; water / 60 °C
2.2: 0.5 h / 20 °C
3.1: isopropyl alcohol; water / 3 h / 20 °C
4.1: potassium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,4-dioxane / 16 h / 50 °C / Schlenk technique; Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; sodium hydrogencarbonate; potassium carbonate;
In
1,4-dioxane; dichloromethane; water; isopropyl alcohol;
DOI:10.1016/j.ejmech.2016.01.042
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: bromine / water
2.1: sulfuric acid / water / 0.5 h / 20 - 172 °C / Microwave irradiation
3.1: dichloromethane
4.1: sodium hydrogencarbonate / isopropyl alcohol; water / 60 °C
4.2: 0.5 h / 20 °C
5.1: isopropyl alcohol; water / 3 h / 20 °C
6.1: potassium carbonate; bis-triphenylphosphine-palladium(II) chloride / water; 1,4-dioxane / 16 h / 50 °C / Schlenk technique; Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; sulfuric acid; bromine; sodium hydrogencarbonate; potassium carbonate;
In
1,4-dioxane; dichloromethane; water; isopropyl alcohol;
DOI:10.1016/j.ejmech.2016.01.042
