2-formamidomethylisoquinoline

Base Information

• Chemical Name: 2-formamidomethylisoquinoline
• CAS No.: 58021-71-9
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.213
• Mol file: 58021-71-9.mol

Synonyms:

Chemical Property of 2-formamidomethylisoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-formamidomethylisoquinoline

There total 1 articles about 2-formamidomethylisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

chloroform (67-66-3,8013-54-5) + 1-(Aminomethyl)isoquinoline dihydrochloride (19382-38-8,1177303-46-6) → 2-formamidomethylisoquinoline (58021-71-9) + Imidazo<5,1-a>isochinolin (234-61-7)

Guidance literature:

With sodium hydroxide; tetra-n-propylammonium bromide; In 1,2-dimethoxyethane; at 50 ℃; for 3.25h;

DOI:10.1021/jo00007a028

Reference yield: 100.0%

2-formamidomethylisoquinoline (58021-71-9) → Imidazo<5,1-a>isochinolin (234-61-7)

Guidance literature:

With triethylamine; trichlorophosphate;

DOI:10.1021/jo00007a028

upstream raw materials:

chloroform

1-(Aminomethyl)isoquinoline dihydrochloride

Downstream raw materials:

Imidazo<5,1-a>isochinolin

Refernces