5,7-dichloro-2-mercapto-6-methylbenzoxazole

Base Information

• Chemical Name: 5,7-dichloro-2-mercapto-6-methylbenzoxazole
• CAS No.: 199293-12-4
• Molecular Formula: C₈H₅Cl₂NOS
• Molecular Weight: 234.106
• Mol file: 199293-12-4.mol

Synonyms:

Chemical Property of 5,7-dichloro-2-mercapto-6-methylbenzoxazole

Chemical Property:

• Boiling Point: 332.4±52.0 °C(Predicted)
• Density: 1.61±0.1 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

5,7-Dichloro-6-methyl-1,3-benzoxazole-2-thiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7-dichloro-2-mercapto-6-methylbenzoxazole

There total 3 articles about 5,7-dichloro-2-mercapto-6-methylbenzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4-Dichloro-3-methyl-6-nitro-phenol (39549-27-4) → 5,7-dichloro-2-mercapto-6-methylbenzoxazole (199293-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂ / 5percent Pt/sulfide carbon / ethyl acetate / 24 h

2: KOH / ethanol / 8 h / Heating

With potassium hydroxide; hydrogen; sulfide carbon; platinum; In ethanol; ethyl acetate;

DOI:10.1021/jm9801004

Reference yield:

2,4-dichloro-3-methylphenol (17788-00-0) → 5,7-dichloro-2-mercapto-6-methylbenzoxazole (199293-12-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / HNO₃, H₂SO₄, AcOH / 2 h / Ambient temperature

2: H₂ / 5percent Pt/sulfide carbon / ethyl acetate / 24 h

3: KOH / ethanol / 8 h / Heating

With potassium hydroxide; sulfuric acid; hydrogen; nitric acid; acetic acid; sulfide carbon; platinum; In ethanol; ethyl acetate;

DOI:10.1021/jm9801004

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 3,5-Dichloro-2-hydroxy-4-methylaniline (40677-44-9) → 5,7-dichloro-2-mercapto-6-methylbenzoxazole (199293-12-4)

Guidance literature:

With potassium hydroxide; In ethanol; for 8h; Heating;

DOI:10.1021/jm9801004

upstream raw materials:

carbon disulfide

3,5-Dichloro-2-hydroxy-4-methylaniline

2,4-Dichloro-3-methyl-6-nitro-phenol

2,4-dichloro-3-methylphenol

Refernces