Technology Process of (R)-2-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid hydrochloride
There total 8 articles about (R)-2-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 89.8 percent / Ba(OH)2 / H2O / 24 h / 125 °C
2: 87 percent / aq. NaOH / 2 h / Ambient temperature
3: DCC / CH2Cl2 / 3 h / Ambient temperature
4: dimethylformamide / 24 h / 50 °C
5: 98 percent / CF3SO3H / 20 h / 80 °C
6: 96.7 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / Ambient temperature
7: 97.4 percent / 37percent aq. HCl / 5 h / 100 °C
With
hydrogenchloride; barium dihydroxide; lithium hydroxide; sodium hydroxide; trifluorormethanesulfonic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19920750522
- Guidance literature:
-
Multi-step reaction with 5 steps
1: DCC / CH2Cl2 / 3 h / Ambient temperature
2: dimethylformamide / 24 h / 50 °C
3: 98 percent / CF3SO3H / 20 h / 80 °C
4: 96.7 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / Ambient temperature
5: 97.4 percent / 37percent aq. HCl / 5 h / 100 °C
With
hydrogenchloride; lithium hydroxide; trifluorormethanesulfonic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1002/hlca.19920750522