Isoxsuprine base

Base Information

• Chemical Name: Isoxsuprine base
• CAS No.: 395-29-9
• Molecular Formula: C₁₈H₂₃NO₃
• Molecular Weight: 301.386
• Mol file: 395-29-9.mol

Synonyms:

Chemical Property of Isoxsuprine base

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Isoxsuprine base

There total 21 articles about Isoxsuprine base which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

3-phenoxy-2-propanone (621-87-4) + p-hydroxynorepherdine (552-85-2) → isoxsuprine (395-28-8,395-29-9)

Guidance literature:

3-phenoxy-2-propanone; p-hydroxynorepherdine; With sodium cyanoborohydride; triethylamine; In methanol; at 20 ℃;

With hydrogenchloride; In water;

Reference yield:

→ isoxsuprine (395-28-8,395-29-9)

Guidance literature:

Gemisch von β(R).γ(R)- und β(S),γ(S)-p-Hydroxy-α-(phenoxy-isopropyl)aminopropiophenon (4), katalytische Tritiierung;

DOI:10.1002/jlcr.2590070402

Reference yield:

(+/-)-p-Hydroxy-norephedrin (552-85-2,771-91-5,1926-72-3,13104-32-0,37692-93-6,52446-53-4,62928-85-2,62928-86-3,73027-12-0) → (-)-Isoxsuprin (395-29-9)

Guidance literature:

Multi-step reaction with 2 steps

2: H₂, AcOH / Adams catalyst / ethanol

With hydrogen; acetic acid; platinum(IV) oxide; In ethanol;

upstream raw materials:

3-phenoxy-2-propanone

p-hydroxynorepherdine

(1RS,2RS)-2-amino-1-(4-hydroxy-phenyl)-propan-1-ol

(1RS,2RS)-2-dibenzylamino-1-(4-benzyloxy-phenyl)-propan-1-ol

Refernces