Technology Process of 3,16α-diacetoxy-6α-hydroxy-1,3,5(10)-estratriene-17-one 17-ethylenedithioketal
There total 4 articles about 3,16α-diacetoxy-6α-hydroxy-1,3,5(10)-estratriene-17-one 17-ethylenedithioketal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 560 mg / CrO3 / acetic acid; H2O / 1) 4 deg C, 30 min, 2) r.t., overnight
2: 290 mg / BF3-etherate / acetic acid / Ambient temperature
3: 1.4 g / HgCl2, CaCO3 / acetonitrile; H2O / 0.5 h / Ambient temperature
4: 140 mg / NaBH4 / tetrahydrofuran; methanol; H2O / 0.5 h / 0 °C
With
chromium(VI) oxide; sodium tetrahydroborate; boron trifluoride diethyl etherate; calcium carbonate; mercury dichloride;
In
tetrahydrofuran; methanol; water; acetic acid; acetonitrile;
DOI:10.1016/0039-128X(82)90056-3
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 290 mg / BF3-etherate / acetic acid / Ambient temperature
2: 1.4 g / HgCl2, CaCO3 / acetonitrile; H2O / 0.5 h / Ambient temperature
3: 140 mg / NaBH4 / tetrahydrofuran; methanol; H2O / 0.5 h / 0 °C
With
sodium tetrahydroborate; boron trifluoride diethyl etherate; calcium carbonate; mercury dichloride;
In
tetrahydrofuran; methanol; water; acetic acid; acetonitrile;
DOI:10.1016/0039-128X(82)90056-3