Iobenguane I-125

Base Information

• Chemical Name: Iobenguane I-125
• CAS No.: 74075-13-1
• Molecular Formula: C₈H₁₀IN₃
• Molecular Weight: 273.188
• UNII: 224T73LR9W
• ChEMBL ID: CHEMBL4584538
• Wikidata: Q27253608
• Mol file: 74075-13-1.mol

Synonyms:Iobenguane I-125;Iobenguane (125I);(125I)metaiodobenzylguanidine;Metaiodobenzylguanidine I-125;(125I)-m-iodobenzylguanidine;UNII-224T73LR9W;224T73LR9W;Guanidine, N-((3-(iodo-(Sup 125)i)phenyl)methyl)-;74075-13-1;CHEMBL4584538;Q27253608

Chemical Property of Iobenguane I-125

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 272.99210
• Heavy Atom Count: 12
• Complexity: 166

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)I)CN=C(N)N
• Isomeric SMILES: C1=CC(=CC(=C1)[125I])CN=C(N)N

Technology Process of Iobenguane I-125

There total 1 articles about Iobenguane I-125 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

m-Iodobenzylguanidine hemisulfate (80663-96-3,103346-16-3) → (m-<125I>iodobenzyl)guanidine (74075-13-1)

Guidance literature:

With ammonium sulfate; sodium (12?I)iodide; In solid; at 140 ℃; for 0.5h; Product distribution; var. additives, var. initial pH, var. iodoaryl and iodophenethyl-guanidines, -amines and -acids;

DOI:10.1021/jo00347a022

upstream raw materials:

m-Iodobenzylguanidine hemisulfate

Refernces