Carbonochloridic acid, 1-(4-methylphenyl)ethyl ester

Base Information

• Chemical Name: Carbonochloridic acid, 1-(4-methylphenyl)ethyl ester
• CAS No.: 140863-24-7
• Molecular Formula: C10H11ClO2
• Molecular Weight: 198.649
• Mol file: 140863-24-7.mol

Synonyms:

Chemical Property of Carbonochloridic acid, 1-(4-methylphenyl)ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonochloridic acid, 1-(4-methylphenyl)ethyl ester

There total 3 articles about Carbonochloridic acid, 1-(4-methylphenyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

bis(trichloromethyl) carbonate (32315-10-9) + CH3C6H4CH(CH3)OH (536-50-5) → 1-(P-tolyl)ethyl chloroformate (140863-24-7)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c9ob00628a

Reference yield:

phosgene (75-44-5) → 1-(P-tolyl)ethyl chloroformate (140863-24-7)

Guidance literature:

With pentane; at -78 - -60 ℃;

DOI:10.2178/jsl/1190150152

Reference yield:

para-methylacetophenone (122-00-9) → 1-(P-tolyl)ethyl chloroformate (140863-24-7)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; sodium tetrahydroborate / 3 h / 0 - 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

With methanol; sodium tetrahydroborate; triethylamine; In dichloromethane;

DOI:10.1039/c9ob00628a

upstream raw materials:

phosgene

para-methylacetophenone

bis(trichloromethyl) carbonate

CH₃C₆H₄CH(CH₃)OH

Downstream raw materials:

1-(1-chloroethyl)-4-methylbenzene

Refernces