3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine

Base Information

• Chemical Name: 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine
• CAS No.: 105214-69-5
• Molecular Formula: C₁₇H₁₄N₂O₂
• Molecular Weight: 278.31
• Mol file: 105214-69-5.mol

Synonyms:

Chemical Property of 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine

There total 3 articles about 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 26.0%

3-(p-Methylphenyl)-1-phenyl-2-nitropropenone (105202-52-6) + potassium cyanide (151-50-8) → 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine (105214-69-5)

Guidance literature:

In ethanol; 1)-10 deg C 2)overnight room temp.;

Reference yield:

butyl-(4-methyl-benzyliden)-amine (7020-93-1) → 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine (105214-69-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent

2: 26 percent / aq. ethanol / 1)-10 deg C 2)overnight room temp.

In ethanol;

Reference yield:

2-nitroacetophenone (614-21-1) → 3-Benzoyl-4-(p-methylphenyl)-5-isoxazolamine (105214-69-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent

2: 26 percent / aq. ethanol / 1)-10 deg C 2)overnight room temp.

In ethanol;

upstream raw materials:

3-(p-Methylphenyl)-1-phenyl-2-nitropropenone

potassium cyanide

butyl-(4-methyl-benzyliden)-amine

2-nitroacetophenone

Refernces