1-(4-amino-benzyl)-[5]isoquinolylamine

Base Information

• Chemical Name: 1-(4-amino-benzyl)-[5]isoquinolylamine
• CAS No.: 855268-36-9
• Molecular Formula: C₁₆H₁₅N₃
• Molecular Weight: 249.315
• Mol file: 855268-36-9.mol

Synonyms:

Chemical Property of 1-(4-amino-benzyl)-[5]isoquinolylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-amino-benzyl)-[5]isoquinolylamine

There total 3 articles about 1-(4-amino-benzyl)-[5]isoquinolylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-nitro-1-(4-nitro-benzyl)-isoquinoline (101727-82-6) → 1-(4-amino-benzyl)-[5]isoquinolylamine (855268-36-9)

Guidance literature:

With ethanol; nickel; Hydrogenation;

Reference yield:

1-benzylisoquinoline (6907-59-1) → 1-(4-amino-benzyl)-[5]isoquinolylamine (855268-36-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; water; nitric acid

2: Raney nickel; ethanol / Hydrogenation

With ethanol; sulfuric acid; water; nitric acid; nickel;

Reference yield:

p-aminophenylacetonitrile (3544-25-0) + 5-amino-1-chloroisoquinoline (374554-54-8) → 1-(4-amino-benzyl)-[5]isoquinolylamine (855268-36-9)

Guidance literature:

With ammonia; potassium amide; Erhitzen des Reaktionsprodukts mit wss. H₂SO₄ auf 170grad;

upstream raw materials:

p-aminophenylacetonitrile

5-amino-1-chloroisoquinoline

5-nitro-1-(4-nitro-benzyl)-isoquinoline

1-benzylisoquinoline

Downstream raw materials:

N-[1-(4-acetylamino-benzyl)-[5]isoquinolyl]-acetamide