2-bromo-3,6-dimethyl-aniline

Base Information

• Chemical Name: 2-bromo-3,6-dimethyl-aniline
• CAS No.: 856352-10-8
• Molecular Formula: C₈H₁₀BrN
• Molecular Weight: 200.078
• Mol file: 856352-10-8.mol

Synonyms:

Chemical Property of 2-bromo-3,6-dimethyl-aniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-bromo-3,6-dimethyl-aniline

There total 5 articles about 2-bromo-3,6-dimethyl-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-1,4-dimethyl-3-nitro-benzene (52415-02-8) → 2-bromo-3,6-dimethyl-aniline (856352-10-8)

Guidance literature:

With sulfuric acid; iron;

DOI:10.1016/S0022-5347(05)67834-2

Reference yield:

4-bromo-2,5-dimethylbenzoic acid (276677-03-3) → 2-bromo-3,6-dimethyl-aniline (856352-10-8)

Guidance literature:

Multi-step reaction with 5 steps

1: fuming sulfuric acid; nitric acid / 95 °C

2: copper chromite; quinoline / 180 - 190 °C

3: tin (II)-chloride; hydrogen chloride; ethanol

4: aq.-ethanolic H₂SO₄ / Diazotization_.Erwaermen der Diazoniumsalz-Loesung auf dem Dampfbad

5: iron; aqueous sulfuric acid

With quinoline; hydrogenchloride; copper chromite; ethanol; sulfuric acid; nitric acid; iron; tin(ll) chloride;

DOI:10.1016/S0022-5347(05)67834-2

Reference yield:

3-bromo-2,5-dimethyl-4-nitro-aniline → 2-bromo-3,6-dimethyl-aniline (856352-10-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic H₂SO₄ / Diazotization_.Erwaermen der Diazoniumsalz-Loesung auf dem Dampfbad

2: iron; aqueous sulfuric acid

With sulfuric acid; iron;

DOI:10.1016/S0022-5347(05)67834-2

upstream raw materials:

2-bromo-1,4-dimethyl-3-nitro-benzene

4-bromo-2,5-dimethylbenzoic acid

3-bromo-1,4-dimethyl-2,5-dinitro-benzene

4-bromo-2,5-dimethyl-3,6-dinitro-benzoic acid

Downstream raw materials:

2,4-dibromo-3,6-dimethylaniline