(1R,2S)-2-nitrocyclohexyl acetate

Base Information

• Chemical Name: (1R,2S)-2-nitrocyclohexyl acetate
• CAS No.: 1242165-56-5
• Molecular Formula: C₈H₁₃NO₄
• Molecular Weight: 187.196
• Mol file: 1242165-56-5.mol

Synonyms:

Chemical Property of (1R,2S)-2-nitrocyclohexyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2S)-2-nitrocyclohexyl acetate

There total 2 articles about (1R,2S)-2-nitrocyclohexyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + cis-2-nitrocyclohexanol (4050-48-0,43138-50-7,108267-18-1,125356-60-7,125356-64-1,125356-65-2,125409-46-3,142235-58-3) → (1R,2S)-2-nitrocyclohexyl acetate (1242165-56-5) + (1S,2R)-2-nitrocyclohexanol

Guidance literature:

With Candida cylindracea C₁ lipase; at 20 - 40 ℃; for 27h; optical yield given as %ee; enantioselective reaction; Resolution of racemate; Enzymatic reaction;

DOI:10.1016/j.tetasy.2010.05.006

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + cis-2-nitrocyclohexanol (4050-48-0,43138-50-7,108267-18-1,125356-60-7,125356-64-1,125356-65-2,125409-46-3,142235-58-3) → (1R,2S)-2-nitrocyclohexyl acetate (1242165-56-5) + (1R,2S)-2-nitrocyclohexanol + (1S,2R)-2-nitrocyclohexanol

Guidance literature:

With Alcaligenes spp. lipase; at 20 - 40 ℃; for 27h; optical yield given as %ee; enantioselective reaction; Resolution of racemate; Enzymatic reaction;

DOI:10.1016/j.tetasy.2010.05.006

upstream raw materials:

vinyl acetate

cis-2-nitrocyclohexanol

Refernces