N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin

Base Information

• Chemical Name: N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin
• CAS No.: 33140-76-0
• Molecular Formula: C₁₆H₁₆N₂O₆S
• Molecular Weight: 364.379
• Mol file: 33140-76-0.mol

Synonyms:

Chemical Property of N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin

There total 5 articles about N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-benzeneethanol (15121-84-3) → N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin (33140-76-0)

Guidance literature:

Multi-step reaction with 4 steps

1: aq. HBr

2: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

3: Py

4: (i) NaH, DMF, (ii) /BRN= 506456/, (iii) aq. NaOH, MeOH

With pyridine; hydrogen bromide;

DOI:10.1139/v71-329

Reference yield:

(2-bromoethyl)-2-nitrobenzene (16793-89-8) → N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin (33140-76-0)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

2: Py

3: (i) NaH, DMF, (ii) /BRN= 506456/, (iii) aq. NaOH, MeOH

With pyridine;

DOI:10.1139/v71-329

Reference yield:

ethyl 2-nitrophenylacetate (31912-02-4) → N-Benzolsulfonyl-N-2-(2-nitrophenyl)-ethylglycin (33140-76-0)

Guidance literature:

Multi-step reaction with 5 steps

1: NaBH₄, AlCl₃

2: aq. HBr

3: (i) aq. NaN₃, DMSO, (ii) Ph₃P, benzene, (iii) aq. HBr, AcOH

4: Py

5: (i) NaH, DMF, (ii) /BRN= 506456/, (iii) aq. NaOH, MeOH

With pyridine; sodium tetrahydroborate; aluminium trichloride; hydrogen bromide;

DOI:10.1139/v71-329

upstream raw materials:

N-Benzolsulfonyl-2-(2-nitrophenyl)-ethylamin

ethyl bromoacetate

2-nitro-benzeneethanol

(2-bromoethyl)-2-nitrobenzene