Technology Process of C18H19NO3
There total 8 articles about C18H19NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 17 h / Inert atmosphere; Reflux
2.1: triethylamine / dichloromethane / 3 h / 20 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux
4.1: sodium hydroxide / chloroform; water / 17 h / 0 - 20 °C
5.1: trichlorophosphate / acetonitrile / 3 h / Inert atmosphere; Reflux
5.2: 16 h / -5 - 20 °C / Inert atmosphere
6.1: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 16 h / 760.05 Torr
7.1: catalase from bovine liver; magnesium chloride / dimethyl sulfoxide / 24 h / 40 °C / pH 9 / Darkness; Enzymatic reaction
With
lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; acetic acid; triethylamine; sodium hydroxide; magnesium chloride; catalase from bovine liver; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; water; dimethyl sulfoxide; acetonitrile;
DOI:10.1002/chem.201201895
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine / dichloromethane / 3 h / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux
3.1: sodium hydroxide / chloroform; water / 17 h / 0 - 20 °C
4.1: trichlorophosphate / acetonitrile / 3 h / Inert atmosphere; Reflux
4.2: 16 h / -5 - 20 °C / Inert atmosphere
5.1: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 16 h / 760.05 Torr
6.1: catalase from bovine liver; magnesium chloride / dimethyl sulfoxide / 24 h / 40 °C / pH 9 / Darkness; Enzymatic reaction
With
lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; acetic acid; triethylamine; sodium hydroxide; magnesium chloride; catalase from bovine liver; trichlorophosphate;
In
tetrahydrofuran; methanol; dichloromethane; chloroform; water; dimethyl sulfoxide; acetonitrile;
DOI:10.1002/chem.201201895
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux
2.1: sodium hydroxide / chloroform; water / 17 h / 0 - 20 °C
3.1: trichlorophosphate / acetonitrile / 3 h / Inert atmosphere; Reflux
3.2: 16 h / -5 - 20 °C / Inert atmosphere
4.1: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 16 h / 760.05 Torr
5.1: catalase from bovine liver; magnesium chloride / dimethyl sulfoxide / 24 h / 40 °C / pH 9 / Darkness; Enzymatic reaction
With
lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; acetic acid; sodium hydroxide; magnesium chloride; catalase from bovine liver; trichlorophosphate;
In
tetrahydrofuran; methanol; chloroform; water; dimethyl sulfoxide; acetonitrile;
DOI:10.1002/chem.201201895