Benzoic acid, 4-[(2-chlorophenyl)thio]-

Base Information

• Chemical Name: Benzoic acid, 4-[(2-chlorophenyl)thio]-
• CAS No.: 141358-09-0
• Molecular Formula: C13H9ClO2S
• Molecular Weight: 264.72700
• Mol file: 141358-09-0.mol

Synonyms:4-(2-Chloro-phenylsulfanyl)-benzoic acid;

Chemical Property of Benzoic acid, 4-[(2-chlorophenyl)thio]-

Chemical Property:

• Boiling Point: 414.1±30.0 °C(Predicted)
• PSA: 62.60000
• Density: 1.42±0.1 g/cm3(Predicted)
• LogP: 4.18940

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Chlorophenylthio)BenzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-[(2-chlorophenyl)thio]-

There total 1 articles about Benzoic acid, 4-[(2-chlorophenyl)thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-chlorothiphenol (6320-03-2) + 4-iodobenzoic acid (619-58-9) → 4-(2-chlorophenylthio)benzoic acid (141358-09-0)

Guidance literature:

With potassium hydroxide; copper; In water; for 9h; Heating;

DOI:10.1135/cccc19920194

Reference yield:

methanesulfonamide (3144-09-0) + 4-(2-chlorophenylthio)benzoic acid (141358-09-0) → 4-(2-chlorophenylthio)-N-(methylsulfonyl)benzamide (1354960-53-4)

Guidance literature:

4-(2-chlorophenylthio)benzoic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 1h;

methanesulfonamide; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

4-(2-chlorophenylthio)benzoic acid (141358-09-0) → 4-(2-Chloro-phenylsulfanyl)-N,N-dimethyl-benzamide

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / SOCl₂ / benzene; dimethylformamide / 2 h / Heating

2: benzene / 2 h

With thionyl chloride; In N,N-dimethyl-formamide; benzene;

DOI:10.1135/cccc19920194

upstream raw materials:

2-chlorothiphenol

4-iodobenzoic acid

Downstream raw materials:

N,N-dimethyl-4-(2-chlorophenylthio)benzylamine

4-(2-chlorophenylthio)-N-(methylsulfonyl)benzamide

Refernces