3,5-Dimethyl-4-hydroxybenzenemethanol

Base Information

• Chemical Name: 3,5-Dimethyl-4-hydroxybenzenemethanol
• CAS No.: 4397-14-2
• Molecular Formula: C9H12 O2
• Molecular Weight: 152.193
• Hs Code.: 2907299090
• Mol file: 4397-14-2.mol

Synonyms:Benzylalcohol, 4-hydroxy-3,5-dimethyl- (6CI,7CI,8CI);2,6-Dimethyl-4-(hydroxymethyl)phenol; 2,6-Dimethyl-4-methylolphenol;3,5-Dimethyl-4-hydroxybenzyl alcohol; 4-(Hydroxymethyl)-2,6-dimethylphenol;4-Hydroxy-3,5-dimethylbenzenemethanol; 4-Hydroxy-3,5-dimethylbenzyl alcohol;4-Methylol-2,6-dimethylphenol; 4-Methylol-2,6-xylenol; NSC 128402; a1,4-Mesitylenediol

Chemical Property of 3,5-Dimethyl-4-hydroxybenzenemethanol

Chemical Property:

• Vapor Pressure: 0.000766mmHg at 25°C
• Boiling Point: 293.8°C at 760 mmHg
• Flash Point: 143.5°C
• PSA: 40.46000
• Density: 1.133g/cm³
• LogP: 1.50130

Purity/Quality:

98%Min ^*data from raw suppliers

4-(Hydroxymethyl)-2,6-dimethylphenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-Dimethyl-4-hydroxybenzenemethanol

There total 20 articles about 3,5-Dimethyl-4-hydroxybenzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-hydroxy-3,5-dimethylbenzaldehyde (2233-18-3) → 4-(hydroxymethyl)-2,6-dimethylphenol (4397-14-2)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃;

DOI:10.1016/j.tetlet.2020.152584

Reference yield: 83.0%

Mesitol (527-60-6) → 4-hydroxy-3,5-dimethylbenzaldehyde (2233-18-3) + 4-(hydroxymethyl)-2,6-dimethylphenol (4397-14-2)

Guidance literature:

With oxygen; horseradish peroxidase; pH=7; electrolysis after 3 F;

DOI:10.3891/acta.chem.scand.53-0745

Reference yield: 76.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2.6-dimethylphenol (576-26-1,25134-01-4) → 4-(hydroxymethyl)-2,6-dimethylphenol (4397-14-2)

Guidance literature:

In water; at 30 ℃; for 2.5h;

DOI:10.1016/S0040-4020(01)87681-X

upstream raw materials:

formaldehyd

2.6-dimethylphenol

Mesitol

4-hydroxy-3,5-dimethylbenzaldehyde

Downstream raw materials:

2,6-dimethyl-[1,4]benzoquinone-4-(4-hydroxy-phenylimine)

Mesitol

4-hydroxy-3,5-dimethylbenzaldehyde

3,5,3',5'-tetramethyl-stilbene-4,4'-diol

Refernces

• 1、 -. "LIPID PRODRUGS OF NEUROSTEROIDS". Paragraph 00584;-00585. . Retrieved 2021/08/13.
• 2、 -. "LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF". Paragraph 00471; 00472. . Retrieved 2020/02/23.