Technology Process of Silane, trichloro(3-fluorophenyl)-
There total 1 articles about Silane, trichloro(3-fluorophenyl)- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
m-Difluorbenzol, HSiCl3, 300-320grad, angeregt. Elektr.;
- Guidance literature:
-
2-bromostyrene;
With
tert.-butyl lithium;
In
diethyl ether; pentane;
at -78 ℃;
for 1h;
Inert atmosphere;
Trichloro(m-fluorophenyl)silan;
In
diethyl ether; pentane;
at -78 - 20 ℃;
for 16.5h;
Inert atmosphere;
With
lithium aluminium tetrahydride;
In
diethyl ether; pentane;
at 0 - 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1002/anie.202113052
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tert.-butyl lithium / diethyl ether; pentane / 1 h / -78 °C / Inert atmosphere
1.2: 16.5 h / -78 - 20 °C / Inert atmosphere
1.3: 1 h / 0 - 20 °C / Inert atmosphere
2.1: 1,5-hexadienerhodium(I)-chloride dimer; (R,R)-(?)-2,3-bis(t-butylmethylphosphino)quinoxaline / chloroform / 0.08 h / 20 °C / Inert atmosphere; Glovebox; Sealed tube
With
(R,R)-(?)-2,3-bis(t-butylmethylphosphino)quinoxaline; 1,5-hexadienerhodium(I)-chloride dimer; tert.-butyl lithium;
In
diethyl ether; chloroform; pentane;
DOI:10.1002/anie.202113052