Heptanamine hydrochloride

Base Information

• Chemical Name: Heptanamine hydrochloride
• CAS No.: 142-93-8
• Molecular Formula: C7H17N.ClH
• Molecular Weight: 151.68
• Mol file: 142-93-8.mol

Synonyms:Heptanamine hydrochloride;Heptylammonium chloride;Heptylamine, hydrochloride;amino-heptane hydrochloride;n-heptylamine hydrochloride;1-Heptanamine hydrochloride;SCHEMBL2867758;NIOSH/MK0959950;SRUKOJDGOUUFRB-UHFFFAOYSA-N;MK09599500

Chemical Property of Heptanamine hydrochloride

Chemical Property:

• Vapor Pressure: 0.36mmHg at 25°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 151.1127773
• Heavy Atom Count: 9
• Complexity: 35.4

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCCCCN.Cl

Technology Process of Heptanamine hydrochloride

There total 9 articles about Heptanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N-Bis(trimethylsilyl)heptylamin (90014-14-5) → Hexamethyldisiloxane (107-46-0) + heptan-1-amine hydrochloride (142-93-8)

Guidance literature:

With hydrogenchloride;

Reference yield: 91.0%

heptanenitrile (629-08-3) → heptan-1-amine hydrochloride (142-93-8)

Guidance literature:

heptanenitrile; With fac-[Mn(1,2-bis(di-n-propylphosphino)ethane)(CO)₃(CH₃)]; hydrogen; In toluene; at 100 ℃; for 18h; under 37503.8 Torr; Autoclave;

With hydrogenchloride; In diethyl ether; Inert atmosphere;

DOI:10.1002/adsc.201901040

Reference yield: 81.0%

heptanamide (628-62-6) → heptan-1-amine hydrochloride (142-93-8)

Guidance literature:

heptanamide; With bis(cyclopentadienyl)dihydrozirconium; 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane; at 20 ℃; for 24h; under 760.051 Torr; Inert atmosphere;

With hydrogenchloride; In diethyl ether; Inert atmosphere;

upstream raw materials:

N,N-Bis(trimethylsilyl)heptylamin

heptyl-trityl-amine

heptanenitrile

1-Bromoheptane

Downstream raw materials:

N-heptylisocyanate

1-heptyl-2-thiourea

Refernces

• 1、 Weber, Stefan,Veiros, Luis F.,Kirchner, Karl. "Old Concepts, New Application – Additive-Free Hydrogenation of Nitriles Catalyzed by an Air Stable Alkyl Mn(I) Complex". supporting information. p. 5412 - 5420. Retrieved 2019/11/13.
• 2、 Neumann, Jacob,Bornschein, Christoph,Jiao, Haijun,Junge, Kathrin,Beller, Matthias. "Hydrogenation of Aliphatic and Aromatic Nitriles Using a Defined Ruthenium PNP Pincer Catalyst". . p. 5944 - 5948. Retrieved 2015/09/22.