Cph-Cha-Dap-Glu-Bph-Leu

Base Information

• Chemical Name: Cph-Cha-Dap-Glu-Bph-Leu
• CAS No.: 1186310-41-7
• Molecular Formula: C₄₁H₅₇BrClN₇O₉
• Molecular Weight: 907.302
• Mol file: 1186310-41-7.mol

Synonyms:

Chemical Property of Cph-Cha-Dap-Glu-Bph-Leu

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cph-Cha-Dap-Glu-Bph-Leu

There total 1 articles about Cph-Cha-Dap-Glu-Bph-Leu which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Fmoc-Leu-OH (35661-60-0) + Fmoc-Glu(OtBu)-OH (71989-18-9) + (S)-3-cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid (135673-97-1) + N-α-tert-butoxycarbonyl-N-β-(9-fluorenylmethoxycarbonyl)-L-diaminopropionic acid (162558-25-0) + Fmoc-4-bromo-L-phenylalanine (198561-04-5) + N-[(9-fluorenyl)methoxycarbonyl]-4-chloro-L-phenylalanine → Cph-Cha-Dap-Glu-Bph-Leu (1186310-41-7)

Guidance literature:

Fmoc-Leu-OH; With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; for 0.416667h; Automated synthesizer; solid phase reaction;

With acetic anhydride; In N,N-dimethyl-formamide; for 0.0833333h; Automated synthesizer; solid phase reaction;

Fmoc-Glu(OtBu)-OH; (S)-3-cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid; N-α-tert-butoxycarbonyl-N-β-(9-fluorenylmethoxycarbonyl)-L-diaminopropionic acid; Fmoc-4-bromo-L-phenylalanine; N-[(9-fluorenyl)methoxycarbonyl]-4-chloro-L-phenylalanine; Further stages;

DOI:10.1016/j.bmc.2009.05.045

upstream raw materials:

Fmoc-Leu-OH

Fmoc-Glu(OtBu)-OH

(S)-3-cyclohexyl-2-(9H-fluoren-9-ylmethoxycarbonylamino)propionic acid

N-α-tert-butoxycarbonyl-N-β-(9-fluorenylmethoxycarbonyl)-L-diaminopropionic acid

Refernces