Benzoyl chloride, 2-(chloroseleno)-

Base Information

• Chemical Name: Benzoyl chloride, 2-(chloroseleno)-
• CAS No.: 1441-85-6
• Molecular Formula: C7H4Cl2OSe
• Molecular Weight: 253.974
• Mol file: 1441-85-6.mol

Synonyms:

Chemical Property of Benzoyl chloride, 2-(chloroseleno)-

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoyl chloride, 2-(chloroseleno)-

There total 16 articles about Benzoyl chloride, 2-(chloroseleno)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,2'-diselanediyl-di-benzoic acid (6512-83-0) → 2-(chloroseleno)benzoyl chloride (1441-85-6)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 3h; Heating;

DOI:10.1002/jlac.199619961108

Reference yield:

anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 2-(chloroseleno)benzoyl chloride (1441-85-6)

Guidance literature:

With disodium diselenide;

DOI:10.1002/chem.200601584

Reference yield:

2-carboxybenzene diazonium chloride (4661-46-5) → 2-(chloroseleno)benzoyl chloride (1441-85-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium diselenide; sodium hydroxide / water / 2 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: thionyl chloride / 6 h / Reflux; Inert atmosphere

With thionyl chloride; sodium diselenide; sodium hydroxide; In water;

DOI:10.1002/chem.201100930

upstream raw materials:

2,2'-diselanediyl-di-benzoic acid

thionyl chloride

phosphorus pentachloride

anthranilic acid

Downstream raw materials:

2-(2,4,6-triisopropylphenyl)-1,2-benzisoselenazol-3(2H)-one

2-(3-hydroxyphenyl)-1.2-benzisoselenazol-3(2H)-one

2-(4-bromophenyl)benzo[d][1,2]selenazol-3(2H)-one

ethyl 2-selenocyanatobenzoate

Refernces

• 1、 Chen, Cheng,Yang, Kewu. "Ebselen bearing polar functionality: Identification of potent antibacterial agents against multidrug-resistant Gram-negative bacteria". . . Retrieved 2019.
• 2、 Bhabak, Krishna P.,Mugesh, Govindasamy. "Synthesis, characterization, and antioxidant activity of some ebselen analogues". . p. 4594 - 4601. Retrieved 2007.
• 3、 Shaaban, Saad,Negm, Amr,Sobh, Mohamed A.,Wessjohann, Ludger A.. "Organoselenocyanates and symmetrical diselenides redox modulators: Design, synthesis and biological evaluation". . p. 190 - 201. Retrieved 2015.
• 4、 Hou, Wen,Huang, Zhi-Xing,Xu, Hong-Gui,Lin, Jing,Zhang, Dong-Mei,Peng, Qun-Long,Lin, Hui,Chang, Yi-Qun,Wang, Long-Hai,Yao, Zhe,Sun, Ping-Hua,Chen, Wei-Min. "Hybrids of arenobufagin and benzoisoselenazol reducing the cardiotoxicity of arenobufagin". . p. 3391 - 3394. Retrieved 2018.
• 5、 -. "Benzoselenazolone compound and application thereof and bactericide". Paragraph 0090; 0120; 0125. . Retrieved 2021/01/24.
• 6、 Fang, Houqin,Huang, Shengshuo,Li, Fangzheng,Liao, Lujian,Liu, Fan,Liu, Qi,Wu, Fang,Wu, Xin-Yan,Xiao, Zhuping,Xu, Jinyi,Yu, Jing,Zhang, Yan-Xia,Zhou, Yueyang. "High-throughput tandem-microwell assay for ammonia repositions FDA-Approved drugs to inhibit Helicobacter pylori urease". . . Retrieved 2021/11/01.