Benzoic acid, 4-methoxy-, 1-naphthalenylmethyl ester

Base Information

• Chemical Name: Benzoic acid, 4-methoxy-, 1-naphthalenylmethyl ester
• CAS No.: 145224-15-3
• Molecular Formula: C19H16O3
• Molecular Weight: 292.334
• Mol file: 145224-15-3.mol

Synonyms:

Chemical Property of Benzoic acid, 4-methoxy-, 1-naphthalenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzoic acid, 4-methoxy-, 1-naphthalenylmethyl ester

There total 4 articles about Benzoic acid, 4-methoxy-, 1-naphthalenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1-iodo-8-methylnaphthalene (199111-38-1) + caesium p-methoxybenzoate → naphthalen-1-ylmethyl 4-methoxybenzoate (145224-15-3)

Guidance literature:

With bis-diphenylphosphinomethane; palladium diacetate; In N,N-dimethyl-formamide; at 120 ℃; for 4h;

DOI:10.1016/j.tet.2008.01.144

Reference yield: 65.0%

para-iodoanisole (696-62-8) + 1-naphthalene methanol (4780-79-4) + oxalic acid (144-62-7,97993-78-7) → naphthalen-1-ylmethyl 4-methoxybenzoate (145224-15-3)

Guidance literature:

With sodium carbonate; In N,N-dimethyl-formamide; at 125 ℃; for 15h;

DOI:10.1002/chem.202101827

Reference yield: 54.0%

α-cyclopropylstyrene (825-76-3) + C16H7Cl4NO5 → naphthalen-1-ylmethyl 4-methoxybenzoate (145224-15-3)

Guidance literature:

With fac-tris(2-(4,6-difluorophenyl)pyridinato,N,C(2'))iridium(III); In dichloromethane; for 36h; regioselective reaction; Irradiation;

DOI:10.1021/acscatal.1c03969

upstream raw materials:

1-iodo-8-methylnaphthalene

1-naphthaldehyde

4-methoxy-benzaldehyde

para-iodoanisole

Downstream raw materials:

1,2-di(1-naphthyl)ethane

1-(methoxymethyl)naphthalene

1-Methylnaphthalene

4-methoxybenzoic acid

Refernces

• 1、 Leng, Lingying,Ready, Joseph M.. "Hydroesterification and difunctionalization of olefins with N-hydroxyphthalimide esters". . p. 13714 - 13720. Retrieved 2021/11/16.
• 2、 Kesharwani, Tanay,Larock, Richard C.. "Benzylic C-H activation and C-O bond formation via aryl to benzylic 1,4-palladium migrations". . p. 6090 - 6102. Retrieved 2008/09/21.