(Z)-3,4-Dimethoxycinnamic acid

Base Information

• Chemical Name: (Z)-3,4-Dimethoxycinnamic acid
• CAS No.: 14737-88-3
• Molecular Formula: C11H12O4
• Molecular Weight: 208.214
• UNII: 1EUC2RA0WK
• Wikidata: Q27887071
• Mol file: 14737-88-3.mol

Synonyms:(Z)-3,4-Dimethoxycinnamic acid;1EUC2RA0WK;14737-88-3;3,4-Dimethoxycinnamic acid, (Z)-;UNII-1EUC2RA0WK;(Z)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid;Cinnamic acid, 3,4-dimethoxy-, (Z)-;(2Z)-3-(3,4-Dimethoxyphenyl)-2-propenoic acid;2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, (2Z)-;2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-, (Z)-;Cinnamic acid, 3,4-dimethoxy-;NSC 4323;EINECS 219-025-5;NSC 43569;AI3-24427;2-Propenoic acid, 3-(3,4-dimethoxyphenyl)-;z-3,4-dimethoxycinnamic acid;Cinnamic acid, 3,4-dimethoxy-, cis-;Q27887071;81EAFE3E-9D74-4DF4-8165-71BA55ADB569

Chemical Property of (Z)-3,4-Dimethoxycinnamic acid

Chemical Property:

• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 208.07355886
• Heavy Atom Count: 15
• Complexity: 237

Purity/Quality:

95%-98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C=CC(=O)O)OC
• Isomeric SMILES: COC1=C(C=C(C=C1)/C=C\C(=O)O)OC

Technology Process of (Z)-3,4-Dimethoxycinnamic acid

There total 3 articles about (Z)-3,4-Dimethoxycinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-dimethoxyphenylpropiolic acid (22511-06-4) → (Z)-3,4-dimethoxycinnamic acid (14737-88-3)

Guidance literature:

With hydrogen; Lindlar's catalyst; In ethanol;

Reference yield:

3,4-dimethoxy-trans-cinnamic acid (14737-89-4) → (Z)-3,4-dimethoxycinnamic acid (14737-88-3)

Guidance literature:

With N-butylamine; In methanol; acetonitrile; for 8h; Reagent/catalyst; Mechanism; UV-irradiation;

DOI:10.1039/d0pp00072h

Reference yield:

→ (Z)-3,4-dimethoxycinnamic acid (14737-88-3)

Guidance literature:

3,4-Dimethoxy-benzaldehyd, Malonsaeure, Py., Piperidin;

upstream raw materials:

3,4-dimethoxyphenylpropiolic acid

3,4-dimethoxy-trans-cinnamic acid

Downstream raw materials:

3,4-dimethoxy-trans-cinnamic acid

(2RS,3SR)-2,3-diacetoxy-3-(3,4-dimethoxy-phenyl)-propionic acid methyl ester

(1RS,2RS)-1-(3,4-dimethoxy-phenyl)-propane-1,2,3-triol

methyl (E)-3-(3,4-dimethoxyphenyl)acrylate

Refernces