4-oxo-pentoyl chloride

Base Information

• Chemical Name: 4-oxo-pentoyl chloride
• CAS No.: 1490-24-0
• Molecular Formula: C5H7ClO2
• Molecular Weight: 134.562
• Mol file: 1490-24-0.mol

Synonyms:levulinic acid chloride;Laevulinoylchloride;levulinyl chloride;4-Oxo-valerylchloride;4-oxopentanoyl chloride;levulinoyl chloride;

Chemical Property of 4-oxo-pentoyl chloride

Chemical Property:

• Boiling Point: 189.5±23.0 °C(Predicted)
• PSA: 34.14000
• Density: 1.153±0.06 g/cm3(Predicted)
• LogP: 1.12100

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-oxo-pentoyl chloride

There total 3 articles about 4-oxo-pentoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

levulinic acid (123-76-2) → 4-oxo-pentanoyl chloride (1490-24-0)

Guidance literature:

With thionyl chloride; at 50 ℃; under 30 Torr;

DOI:10.1016/j.ica.2017.07.027

Reference yield:

oxalyl dichloride (79-37-8) → 4-oxo-pentanoyl chloride (1490-24-0)

Guidance literature:

In dichloromethane;

Reference yield:

→ 4-oxo-pentanoyl chloride (1490-24-0)

Guidance literature:

DOI:10.1021/jo01073a021

upstream raw materials:

levulinic acid

oxalyl dichloride

Downstream raw materials:

1-(4-methoxyphenyl)pentane-1,4-dione

4-methoxyphenyl 6-O-levulinoyl-2,3,4-tri-O-p-toluoyl-β-D-glucopyranoside

(S)-N-(4-Oxo-valeryl)-N-[(2'-cyano-biphenyl-4-yl)methyl]valine benzyl ester

4,4-diphenyl-valeric acid

Refernces

• 1、 Choi, Myung Gil,Hwang, Jiyoung,Moon, Jung Ok,Sung, Jaeyoung,Chang, Suk-Kyu. "Hydrazine-selective chromogenic and fluorogenic probe based on levulinated coumarin". . p. 5260 - 5263. Retrieved 2011.
• 2、 Beemelmanns, Christine,Reissig, Hans-Ulrich. "Highly diastereoselective samarium diiodide induced cyclizations of new 3-substituted indole derivatives". . p. 4475 - 4480. Retrieved 2009.
• 3、 Candu, Natalia,Paul, Diana,Marcu, Ioan-Cezar,Tudorache, Madalina,Parvulescu, Vasile I.,Coman, Simona M.. "New organic-inorganic LDH composites: Synthesis, characterization and catalytic behavior in the green epoxidation of α, β-unsaturated esters". . p. 127 - 132. Retrieved 2017/10/05.