Ethylene phosphate

Base Information

• Chemical Name: Ethylene phosphate
• CAS No.: 6711-47-3
• Molecular Formula: C2H5 O4 P
• Molecular Weight: 124.033
• DSSTox Substance ID: DTXSID001315898
• Nikkaji Number: J2.018.723I,J298.411C
• Mol file: 6711-47-3.mol

Synonyms:ethylene phosphate;ethylene hydrogen phosphate;6711-47-3;SCHEMBL811704;UYXQLQUXXCIFQM-UHFFFAOYSA-N;DTXSID001315898

Chemical Property of Ethylene phosphate

Chemical Property:

• PSA: 65.57000
• LogP: 0.13360
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 123.99254563
• Heavy Atom Count: 7
• Complexity: 100

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COP(=O)(O1)O

Technology Process of Ethylene phosphate

There total 3 articles about Ethylene phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-1,3,2-dioxaphospholane-2-oxide (2196-04-5) → phosphoric acid mono-(2-hydroxy-ethyl) ester (1892-26-8) + methyl 2-hydroxyethyl phosphate (67846-69-9) + 2-oxo-2λ5-[1,3,2]dioxaphospholan-2-ol (6711-47-3)

Guidance literature:

With sodium hydroxide; Rate constant; Kinetics; Mechanism; Ambient temperature; determination of 18O-labeled intermediates; pH-product profiles (ratios analyzed by 31P-NMR);

DOI:10.1021/jo00197a041

Reference yield:

ethylene glycol (107-21-1) → phosphoric acid mono-(2-hydroxy-ethyl) ester (1892-26-8) + 2-oxo-2λ5-[1,3,2]dioxaphospholan-2-ol (6711-47-3) + phosphoric acid bis-(2-hydroxy-ethyl) ester (18924-97-5)

Guidance literature:

With pyrophosphoric acid; at 100 ℃; for 1h; Yield given;

DOI:10.1246/bcsj.54.1891

Reference yield:

ethyl ethylene phosphate (823-31-4) → phosphoric acid mono-(2-hydroxy-ethyl) ester (1892-26-8) + 2-oxo-2λ5-[1,3,2]dioxaphospholan-2-ol (6711-47-3) + ethyl (2-hydroxyethyl) hydrogen phosphate (5178-07-4)

Guidance literature:

With sodium hydroxide; sulfuric acid; water-d2; In 1,4-dioxane; Rate constant; Kinetics; Mechanism; Ambient temperature; determination of 18O-labeled intermediates; pH-product profiles (ratios analyzed by 31P-NMR);

DOI:10.1021/jo00197a041

upstream raw materials:

2-methoxy-1,3,2-dioxaphospholane-2-oxide

ethyl ethylene phosphate

ethylene glycol

Refernces

• 1、 Yamaguchi, Hachiro,Ogura, Fumio,Otsubo, Tetsuo,Ikeura, Yasuhiro. "Phosphorylation with Pyrophosphoric Acid". . p. 1891 - 1892. Retrieved 2007/10/02.