Technology Process of 2-[2-(acetylamino)-6-oxo-3,6-dihydropyrimidin-4-yl]-2-oxoethyl methyl carbonate
There total 6 articles about 2-[2-(acetylamino)-6-oxo-3,6-dihydropyrimidin-4-yl]-2-oxoethyl methyl carbonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 42 percent / ethanol / 17 h / Heating
2: 67 percent / 0.17 h / 100 °C
3: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
4: 86 percent / 2 h / Heating
5: 901 mg / pyridine / 1.5 h / 0 °C
6: 1.) 88percent formic acid, 2.) Ac2O / 1) 100 deg C, 30 min, 2) 100 deg C, 5 min
With
pyridine; formic acid; o-toluenesulfonic acid; acetic anhydride;
In
ethanol; xylene;
DOI:10.1021/jo00169a001
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 67 percent / 0.17 h / 100 °C
2: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
3: 86 percent / 2 h / Heating
4: 901 mg / pyridine / 1.5 h / 0 °C
5: 1.) 88percent formic acid, 2.) Ac2O / 1) 100 deg C, 30 min, 2) 100 deg C, 5 min
With
pyridine; formic acid; o-toluenesulfonic acid; acetic anhydride;
In
xylene;
DOI:10.1021/jo00169a001
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 95 percent / toluenesulfonic acid / xylene / 0.25 h / Heating
2: 86 percent / 2 h / Heating
3: 901 mg / pyridine / 1.5 h / 0 °C
4: 1.) 88percent formic acid, 2.) Ac2O / 1) 100 deg C, 30 min, 2) 100 deg C, 5 min
With
pyridine; formic acid; o-toluenesulfonic acid; acetic anhydride;
In
xylene;
DOI:10.1021/jo00169a001
