cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone

Base Information

• Chemical Name: cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone
• CAS No.: 102171-45-9
• Molecular Formula: C₁₉H₂₀O₂
• Molecular Weight: 280.367
• Mol file: 102171-45-9.mol

Synonyms:

Chemical Property of cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone

There total 3 articles about cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-3-[4-(methoxy)phenyl]cyclopent-2-ene-1-one (20935-29-9) → cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone (102171-45-9)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium/CaCO₃; methanol.KOH / Hydrogenation

2: aqueous HBr; acetic acid

3: K₂CO₃; 1-phenyl-ethanone

With potassium hydroxide; Lindlar's catalyst; hydrogen bromide; potassium carbonate; acetic acid; acetophenone;

Reference yield:

3-(4-methoxyphenyl)-2-methylcyclopentan-1-one (20935-32-4,117926-41-7) → cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone (102171-45-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous HBr; acetic acid

2: K₂CO₃; 1-phenyl-ethanone

With hydrogen bromide; potassium carbonate; acetic acid; acetophenone;

Reference yield:

2-Bromo-4'-methoxyacetophenone (2632-13-5) → cis-3-(4-benzyloxy-phenyl)-2-methyl-cyclopentanone (102171-45-9)

Guidance literature:

Multi-step reaction with 4 steps

2: palladium/CaCO₃; methanol.KOH / Hydrogenation

3: aqueous HBr; acetic acid

4: K₂CO₃; 1-phenyl-ethanone

With potassium hydroxide; Lindlar's catalyst; hydrogen bromide; potassium carbonate; acetic acid; acetophenone;

upstream raw materials:

2-methyl-3-[4-(methoxy)phenyl]cyclopent-2-ene-1-one

3-(4-methoxyphenyl)-2-methylcyclopentan-1-one

2-Bromo-4'-methoxyacetophenone