2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE

Base Information

• Chemical Name: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE
• CAS No.: 40016-70-4
• Molecular Formula: C₁₁H₁₀N₂O₄
• Molecular Weight: 234.211
• Hs Code.: 2933990090
• Mol file: 40016-70-4.mol

Synonyms:2-Methyl-3-(carbomethoxy)quinoxaline1,4-dioxide; 3-(Methoxycarbonyl)-2-methylquinoxaline 1,4-dioxide;3-Methyl-2-quinoxalinecarboxylic acid methyl ester, N,N'-dioxide; NSC 330180

Chemical Property of 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE

Chemical Property:

• Melting Point: 171oC
• PSA: 77.22000
• LogP: 1.79180

Purity/Quality:

98%min ^*data from raw suppliers

2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE

There total 4 articles about 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide (13297-18-2) → 2-methoxycarbonyl-3-methylquinoxaline 1,4-dioxide (40016-70-4)

Guidance literature:

With triethylamine; calcium chloride; In methanol; at 50 ℃; for 2h;

Reference yield: 32.0%

benzofurazan oxide (480-96-6,68100-26-5) + acetoacetic acid methyl ester (105-45-3) → 2-methoxycarbonyl-3-methylquinoxaline 1,4-dioxide (40016-70-4)

Guidance literature:

With silica gel; for 0.0666667h; Microwave irradiation;

DOI:10.3987/COM-08-11588

Reference yield:

benzofurazan oxide (480-96-6,68100-26-5) + methyl 3-aminocrotonate (14205-39-1) → 2-methoxycarbonyl-3-methylquinoxaline 1,4-dioxide (40016-70-4)

Guidance literature:

In methanol; for 50h; Heating;

DOI:10.1248/cpb.29.110

upstream raw materials:

benzofurazan oxide

acetoacetic acid methyl ester

methyl 3-aminocrotonate

2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide

Downstream raw materials:

methyl 3-methylquinoxaline-2-carboxylate

2-Methylchinoxalin-3-carbonsaeuremethylester-1-oxid

3-Methylchinoxalin-2-carbonsaeuremethylester-1-oxid

Refernces

• 1、 Gomes, Jose R. B.,Monteiro, Andre R.,Campos, Bruno B.,Gomes, Paula,Ribeiro Da Silva, Maria D. M. C.. "The enthalpies of dissociation of the N-O bonds in two quinoxaline derivatives". experimental part. p. 17 - 23. Retrieved 2009/07/26.
• 2、 Acree Jr.,Powell, Joyce R.,Tucker, Sheryl A.,Ribeiro da Silva, Maria D.M.C.,Matos, M. Agostinha R.,Goncalves,Santos,Morais,Pilcher. "Thermochemical and Theoretical Study of Some Quinoxaline 1,4-Dioxides and of Pyrazine 1,4-Dioxide". . p. 3722 - 3726. Retrieved 2007/10/03.