2-Anthracenesulfonic acid, 1-amino-4-[(4-amino-3-sulfophenyl)amino]-9,10-dihydro-9,10-dioxo-, disodium salt

Base Information

• Chemical Name: 2-Anthracenesulfonic acid, 1-amino-4-[(4-amino-3-sulfophenyl)amino]-9,10-dihydro-9,10-dioxo-, disodium salt
• CAS No.: 15827-21-1
• Molecular Formula: C₂₀H₁₃N₃O₈S₂*2Na
• Molecular Weight: 533.45
• Mol file: 15827-21-1.mol

Synonyms:

Chemical Property of 2-Anthracenesulfonic acid, 1-amino-4-[(4-amino-3-sulfophenyl)amino]-9,10-dihydro-9,10-dioxo-, disodium salt

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Anthracenesulfonic acid, 1-amino-4-[(4-amino-3-sulfophenyl)amino]-9,10-dihydro-9,10-dioxo-, disodium salt

There total 4 articles about 2-Anthracenesulfonic acid, 1-amino-4-[(4-amino-3-sulfophenyl)amino]-9,10-dihydro-9,10-dioxo-, disodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

sodium 1-amino-4-bromoanthraquinone-2-sulfonate (6258-06-6) + 2,5-diaminobenzenesulfonic acid sodium salt → disodium 1-amino-4-(4-amino-3-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate (15827-21-1,32866-11-8,116679-68-6)

Guidance literature:

With copper(l) chloride; In water; at 20 ℃; for 4h;

Reference yield: 48.0%

2,5-diaminobenzenesulfonic acid (88-45-9) + sodium 1-amino-4-bromoanthraquinone-2-sulfonate (6258-06-6) → disodium 1-amino-4-(4-amino-3-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate (15827-21-1,32866-11-8,116679-68-6)

Guidance literature:

With sodium carbonate; copper(l) chloride; sodium sulfite; In water; at 20 ℃; for 8h;

DOI:10.1016/j.ejmech.2005.07.007

Reference yield: 32.0%

1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid (116-81-4) + 2,5-diaminobenzenesulfonic acid (88-45-9) → disodium 1-amino-4-(4-amino-2-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate (20349-48-8) + disodium 1-amino-4-(4-amino-3-sulfophenylamino)-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate (15827-21-1,32866-11-8,116679-68-6)

Guidance literature:

With copper; at 120 ℃; for 0.333333h; aq. phosphate buffer; Microwave irradiation;

DOI:10.1021/jm9003297

upstream raw materials:

2,5-diaminobenzenesulfonic acid

sodium 1-amino-4-bromoanthraquinone-2-sulfonate

1-amino-4-bromo-9,10-dioxoanthracene-2-sulphonic acid

Refernces

• 1、 Baqi, Younis,Hausmann, Ralf,Rosefort, Christiane,Rettinger, Jürgen,Schmalzing, Günther,Müller, Christa E.. "Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor". experimental part. p. 817 - 830. Retrieved 2011/04/15.
• 2、 Gl?nzel, Markus,Bültmann, Ralph,Starke, Klaus,Frahm, August W.. "Structure-activity relationships of novel P2-receptor antagonists structurally related to Reactive Blue 2". . p. 1262 - 1276. Retrieved 2007/10/03.