lysergic acid ethyl-2-trityloxyethylamide

Base Information

• Chemical Name: lysergic acid ethyl-2-trityloxyethylamide
• CAS No.: 75074-69-0
• Molecular Formula: C₃₉H₃₉N₃O₂
• Molecular Weight: 581.758
• Mol file: 75074-69-0.mol

Synonyms:

Chemical Property of lysergic acid ethyl-2-trityloxyethylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of lysergic acid ethyl-2-trityloxyethylamide

There total 2 articles about lysergic acid ethyl-2-trityloxyethylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trityl chloride (76-83-5) → lysergic acid ethyl-2-trityloxyethylamide (75074-69-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / NaH / 2 h / Ambient temperature

2: 1.) Ph₃PO*imidazole / 1.) acetonitrile, HMPA, room temperature, 2.) overnight

With sodium hydride; imidazole-triphenylphosphine oxide complex;

Reference yield:

ethyl-2-trityloxyethylamine (75074-68-9) + lysergide (50-37-3) → lysergic acid ethyl-2-trityloxyethylamide (75074-69-0)

Guidance literature:

With imidazole-triphenylphosphine oxide complex; Yield given. Multistep reaction; 1.) acetonitrile, HMPA, room temperature, 2.) overnight;

upstream raw materials:

ethyl-2-trityloxyethylamine

lysergide

trityl chloride

Refernces