Benzenesulfonyl chloride, 2-chloro-3-nitro-

Base Information

• Chemical Name: Benzenesulfonyl chloride, 2-chloro-3-nitro-
• CAS No.: 15945-25-2
• Molecular Formula: C6H3Cl2NO4S
• Molecular Weight: 256.066
• Mol file: 15945-25-2.mol

Synonyms:2-Chlor-3-nitrobenzolsulfonylchlorid;chloro-nitro-benzenesulphonyl chloride;2-Chloro-3-nitro-benzenesulfonyl chloride;

Chemical Property of Benzenesulfonyl chloride, 2-chloro-3-nitro-

Chemical Property:

• Melting Point: 73 - 74 °C
• Boiling Point: 374.6±32.0 °C(Predicted)
• PSA: 88.34000
• Density: 1.708±0.06 g/cm3(Predicted)
• LogP: 3.77970

Purity/Quality:

98% ^*data from raw suppliers

2-Chloro-3-nitrobenzene-1-sulfonylchloride 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenesulfonyl chloride, 2-chloro-3-nitro-

There total 4 articles about Benzenesulfonyl chloride, 2-chloro-3-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-chloro-3-nitroaniline (3970-41-0) → 2-chloro-3-nitrobenzenesulfonyl chloride (15945-25-2)

Guidance literature:

2-chloro-3-nitroaniline; With hydrogenchloride; sodium nitrite; In water; for 0.5h;

With hydrogenchloride; copper(II) sulfate; sodium sulfite; In water; for 0.5h;

DOI:10.1016/S0040-4020(99)01019-4

Reference yield:

2,6-dinitroaniline (606-22-4) → 2-chloro-3-nitrobenzenesulfonyl chloride (15945-25-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium nitrite; sulfuric acid; acetic acid

1.2: CuCl

2.1: 62 percent / glacial acetic acid; iron / 2.5 h / Heating

3.1: hydrochloric acid; sodium nitrite / H₂O / 0.5 h

3.2: 83 percent / Na₂SO₃; CuSO₄; HCl / H₂O / 0.5 h

With hydrogenchloride; sulfuric acid; iron; acetic acid; sodium nitrite; In water; 1.1: Diazotization / 1.2: Chlorination / 2.1: Reduction / 3.1: Diazotization / 3.2: Substitution;

DOI:10.1016/S0040-4020(99)01019-4

Reference yield:

1-chloro-2,6-dinitrobenzene (606-21-3) → 2-chloro-3-nitrobenzenesulfonyl chloride (15945-25-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 62 percent / glacial acetic acid; iron / 2.5 h / Heating

2.1: hydrochloric acid; sodium nitrite / H₂O / 0.5 h

2.2: 83 percent / Na₂SO₃; CuSO₄; HCl / H₂O / 0.5 h

With hydrogenchloride; iron; acetic acid; sodium nitrite; In water; 1.1: Reduction / 2.1: Diazotization / 2.2: Substitution;

DOI:10.1016/S0040-4020(99)01019-4

upstream raw materials:

2-chloro-3-nitroaniline

2,6-dinitroaniline

1-chloro-2,6-dinitrobenzene

Downstream raw materials:

bis(2-chloro-3-nitrophenyl)disulfide

4-chloro-N,N-dimethyl-3-nitrobenzenesulfonamide

Refernces