hexyl phenylcarbamate

Base Information

• Chemical Name: hexyl phenylcarbamate
• CAS No.: 7461-26-9
• Molecular Formula: C13H19 N O2
• Molecular Weight: 221.299
• Mol file: 7461-26-9.mol

Synonyms:Carbamicacid, phenyl-, hexyl ester (9CI); Carbanilic acid, hexyl ester (7CI); Hexylalcohol, carbanilate (6CI); Hexyl N-phenylcarbamate; Hexyl phenylcarbamate; NSC404799

Chemical Property of hexyl phenylcarbamate

Chemical Property:

• Vapor Pressure: 0.00317mmHg at 25°C
• Boiling Point: 283.4°Cat760mmHg
• Flash Point: 125.2°C
• Density: 1.046g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of hexyl phenylcarbamate

There total 9 articles about hexyl phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzoyl azide (582-61-6) + hexan-1-ol (111-27-3) → hexyl N-phenyl-carbamate (7461-26-9)

Guidance literature:

In benzene; at 110 ℃; for 1h; Temperature; Solvent; Flow reactor;

DOI:10.1002/ejoc.201700906

Reference yield: 76.0%

carbon dioxide (124-38-9,18923-20-1) + 4-methylbenzenesulfonic acid n-hexylester (3839-35-8) + aniline (62-53-3) → hexyl N-phenyl-carbamate (7461-26-9)

Guidance literature:

carbon dioxide; aniline; In dimethyl sulfoxide; at 60 ℃; for 0.5h;

With N-benzyl-trimethylammonium hydroxide; In dimethyl sulfoxide; at 60 ℃; for 0.5h;

4-methylbenzenesulfonic acid n-hexylester; In dimethyl sulfoxide; at 60 ℃; for 4h;

DOI:10.1007/s00706-005-0452-2

Reference yield: 75.0%

carbon monoxide (201230-82-2) + aniline (62-53-3) + hexan-1-ol (111-27-3) → hexyl N-phenyl-carbamate (7461-26-9)

Guidance literature:

With Oxone; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In toluene; at 20 - 100 ℃; Schlenk technique; Cooling with liquid nitrogen;

DOI:10.1039/c6cc09133d

upstream raw materials:

n-hexyl chloroformate

aniline

phenyl isocyanate

hexan-1-ol

Refernces

• 1、 Chaturvedi, Devdutt,Ray, Suprabhat. "Triton-B catalyzed, efficient, one-pot synthesis of carbamate esters from alcoholic tosylates". . p. 459 - 463. Retrieved 2006.
• 2、 Iturmendi, Amaia,Iglesias, Manuel,Munárriz, Julen,Polo, Victor,Pérez-Torrente, Jesús J.,Oro, Luis A.. "Efficient preparation of carbamates by Rh-catalysed oxidative carbonylation: unveiling the role of the oxidant". supporting information. p. 404 - 407. Retrieved 2017/01/03.
• 3、 Krutikov,Erkin,Tets,Shmarov. "(4-Arylsulfamoyl)phenylcarbamic acid esters: I. Synthesis and activity against herpes viruses". . p. 1567 - 1573. Retrieved 2016/08/26.