Technology Process of 7-Chlorobenzo[b]thiophene-3-Methanol
There total 4 articles about 7-Chlorobenzo[b]thiophene-3-Methanol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2,2'-((7-chlorobenzo[b]thiophen-3-yl)methylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane);
With
potassium tert-butylate;
In
tetrahydrofuran;
at 20 ℃;
for 0.25h;
Inert atmosphere;
With
sodium perborate hexahydrate; water;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/jacs.0c03197
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
2.1: [Au2(μ-bis(diphenylphosphino)methane)2](OTf)2; sodium carbonate / acetonitrile / 15 h / Inert atmosphere; Irradiation; Glovebox
3.1: potassium tert-butylate / tetrahydrofuran / 0.25 h / 20 °C / Inert atmosphere
3.2: 1 h / 20 °C / Inert atmosphere
With
potassium tert-butylate; [Au2(μ-bis(diphenylphosphino)methane)2](OTf)2; sodium carbonate; potassium carbonate;
In
tetrahydrofuran; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jacs.0c03197
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: [Au2(μ-bis(diphenylphosphino)methane)2](OTf)2; sodium carbonate / acetonitrile / 15 h / Inert atmosphere; Irradiation; Glovebox
2.1: potassium tert-butylate / tetrahydrofuran / 0.25 h / 20 °C / Inert atmosphere
2.2: 1 h / 20 °C / Inert atmosphere
With
potassium tert-butylate; [Au2(μ-bis(diphenylphosphino)methane)2](OTf)2; sodium carbonate;
In
tetrahydrofuran; acetonitrile;
DOI:10.1021/jacs.0c03197