1-METHYL-4-((E)-STYRYL)-BENZENE

Base Information

• Chemical Name: 1-METHYL-4-((E)-STYRYL)-BENZENE
• CAS No.: 1657-45-0
• Molecular Formula: C15H14
• Molecular Weight: 194.276
• Mol file: 1657-45-0.mol

Synonyms:Benzene, 1-methyl-4-(2-phenylethenyl)-, (Z)-;1-methyl-4[(1Z)-2-phenylethenyl]benzene;(Z)-1-(4-methylphenyl)-2-phenylethene;1-Methyl-4-((Z)-styryl)-benzene;Z-1-phenyl-2-(4'-methylphenyl)ethene;1-METHYL-4-((E)-STYRYL)-BENZENE;1-methyl-4-[(Z)-2-phenylethenyl]benzene;1-(4-methylphenyl)-2-phenylethene;(Z)-1-phenyl-2-(p-methylphenyl)ethene;

Chemical Property of 1-METHYL-4-((E)-STYRYL)-BENZENE

Chemical Property:

• Vapor Pressure: 0.00134mmHg at 25°C
• Melting Point: 116-118 °C
• Boiling Point: 121 °C (1 mmHg)
• PSA: 0.00000
• Density: 1.028±0.06 g/cm3(Predicted)
• LogP: 4.16540

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-METHYL-4-((E)-STYRYL)-BENZENE

There total 471 articles about 1-METHYL-4-((E)-STYRYL)-BENZENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + toluene-4-sulfonic acid hydrazide (1576-35-8) → (4,4'-dimethyl-1,1'-biphenyl) (613-33-2) + E-1-methyl-4-styryl-benzene (4714-21-0,130059-91-5,130059-95-9,1657-45-0,1860-17-9)

Guidance literature:

With oxygen; palladium diacetate; In nitromethane; dimethyl sulfoxide; at 70 ℃; for 5h; under 760.051 Torr; optical yield given as %de; stereoselective reaction;

DOI:10.1002/chem.201103671

Reference yield: 72.0%

4-Methylbenzyl alcohol (589-18-4) + Benzyl phenyl sulfone (3112-88-7) → E-1-methyl-4-styryl-benzene (4714-21-0,130059-91-5,130059-95-9,1657-45-0,1860-17-9) + potassium benzenesulfonate (934-55-4)

Guidance literature:

With C₂₄H₂₀ClN₂OPRu; potassium tert-butylate; In 1,4-dioxane; at 125 ℃; for 5h; Inert atmosphere; Schlenk technique; Glovebox;

DOI:10.1002/anie.201407281

Reference yield: 49.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + (4-methylphenyl)azo 4-methylphenyl sulfone (33604-67-0) → (4,4'-dimethyl-1,1'-biphenyl) (613-33-2) + E-1-methyl-4-styryl-benzene (4714-21-0,130059-91-5,130059-95-9,1657-45-0,1860-17-9) + 1-phenyl-1-p-tolyl-ethylene (948-55-0) + 2-phenyl-2-(p-tolylhydrazono)ethyl p-tolyl sulfone

Guidance literature:

tetrakis(triphenylphosphine) palladium⁽⁰⁾; In benzene; at 80 ℃; for 2h; Further byproducts given;

DOI:10.1246/bcsj.61.3575

upstream raw materials:

4-methylphenyl cinnamate

1-(4-methylphenyl)-2-phenylethanol

phenyl-4-methylphenylbenzaldehyde azine

(E)-3-phenylacrylic acid

Downstream raw materials:

1-(4-trans-styryl-benzyl)-pyridinium; bromide

4-methylbibenzyl

diethyl-(4-trans-styryl-benzyl)-amine

dipropyl-(4-trans-styryl-benzyl)-amine

Refernces

• 1、 Biajoli, André F. P.,Fajardo, André R.,Lemos, Thalia S. A.,de Souza, Jaqueline F.. "Phosphine-Functionalized Chitosan Microparticles as Support Materials for Palladium Nanoparticles in Heck Reactions". . . Retrieved 2022/01/11.
• 2、 Ojha, Subhadra,Panda, Niranjan. "Pd-Catalyzed desulfitative arylation of olefins by: N -methoxysulfonamide". supporting information. p. 1292 - 1298. Retrieved 2022/02/19.