N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester

Base Information

• Chemical Name: N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester
• CAS No.: 95782-60-8
• Molecular Formula: C₂₄H₃₀N₂O₆
• Molecular Weight: 442.512
• Mol file: 95782-60-8.mol

Synonyms:

Chemical Property of N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester

There total 2 articles about N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(benzyloxycarbonyl)-D-serine (6081-61-4) + L-leucine benzyl ester hydrochloride (2462-35-3) → N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester (95782-60-8)

Guidance literature:

With tetrahydrofuran; triethylamine; dicyclohexyl-carbodiimide; weiteres Reagens: Acetonitril;

Reference yield:

Z-DL-serine (2768-56-1) → N-(N-benzyloxycarbonyl-L-seryl)-L-leucine benzyl ester (2767-17-1) + N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester (95782-60-8)

Guidance literature:

With tetrahydrofuran; triethylamine; dicyclohexyl-carbodiimide; weiteres Reagens: Acetonitril;

Reference yield:

N-(N-benzyloxycarbonyl-D-seryl)-L-leucine benzyl ester (95782-60-8) + chlorophosphoric acid diphenyl ester (2524-64-3) → N-(O-phosphono-D-seryl)-L-leucine (6665-27-6) + N-[O-(hydroxy-phenoxy-phosphoryl)-D-seryl]-L-leucine

Guidance literature:

With pyridine; Hydrierung des Reaktionsprodukts an Palladium/Kohle in wss. Aethanol und anschliessend an Platin in Essigsaeure;

upstream raw materials:

N-(benzyloxycarbonyl)-D-serine

L-leucine benzyl ester hydrochloride

Z-DL-serine

Downstream raw materials:

N-(O-phosphono-D-seryl)-L-leucine