2,2',2''-Nitrilotriacetic acid triethyl ester

Base Information

• Chemical Name: 2,2',2''-Nitrilotriacetic acid triethyl ester
• CAS No.: 16669-54-8
• Molecular Formula: C12H21NO6
• Molecular Weight: 275.302
• Hs Code.: 2921199090
• Mol file: 16669-54-8.mol

Synonyms:Triglykolamidsaeure-triaethylester;nitrilotri-acetic acid triethyl ester;Nitrilotri-essigsaeure-triaethylester;tris(ethoxycarbonylmethyl)amine;triethyl nitrilotriacetate;nitrilotriacetic acid triethyl ester;

Chemical Property of 2,2',2''-Nitrilotriacetic acid triethyl ester

Chemical Property:

• Boiling Point: 184 °C(Press: 17 Torr)
• PKA: 2.62±0.50(Predicted)
• PSA: 82.14000
• Density: 1.1182 g/cm3(Temp: 9.5 °C)
• LogP: -0.02230
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

NITRILOTRIACETIC ACID TRIETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2',2''-Nitrilotriacetic acid triethyl ester

There total 5 articles about 2,2',2''-Nitrilotriacetic acid triethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

nitrilotriacetic acid (139-13-9,80751-51-5) + ethanol (64-17-5) → triethyl nitrilotriacetate (16669-54-8)

Guidance literature:

sulfuric acid; for 8h; reflux;

DOI:10.1080/00397919808004458

Reference yield:

diazoacetic acid ethyl ester (623-73-4) → triethyl nitrilotriacetate (16669-54-8) + Diethyl maleate (141-05-9)

Guidance literature:

With ammonia; porphyrin iron complex; In tetrahydrofuran; at 25 ℃; for 5h;

DOI:10.1039/b609265a

Reference yield:

diazoacetic acid ethyl ester (623-73-4) → triethyl nitrilotriacetate (16669-54-8)

Guidance literature:

With ammonium acetate; porphyrin iron complex; In tetrahydrofuran; at 25 ℃; for 0.166667h;

DOI:10.1039/b609265a

upstream raw materials:

nitrilotriacetic acid

ethanol

ethyl iodide

diazoacetic acid ethyl ester

Downstream raw materials:

nitrilotriacetic acid triamide

Refernces

• 1、 Bhattacharjee, Manish,Datta, Riya. "Synthesis of a new macrocyclic ligand with six amide receptor sites". . p. 3579 - 3580. Retrieved 1996.
• 2、 -. "Friction modifier and their use in lubricants and fuels". Page/Page column 29. . Retrieved 2016/01/09.
• 3、 -. "Resist composition and patterning process". . . Retrieved 2010/02/17.