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Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-

Base Information Edit
  • Chemical Name:Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
  • CAS No.:6296-53-3
  • Molecular Formula:C10H7NO4
  • Molecular Weight:205.17
  • Hs Code.:
  • Mol file:6296-53-3.mol
Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-

Synonyms:Phthalicanhydride, 3-acetamido- (6CI,8CI);3-Acetamidophthalic anhydride;3-Acetylaminophthalic anhydride;NSC 16261;NSC 17048;AC1L5EJ7;AC1Q6H8C;n-(1,3-Dioxo-1,3-dihydro-2-benzofuran-4-yl)acetamide;AKOS002687661;N-(1,3-dioxo-2-benzofuran-4-yl)acetamide;

Suppliers and Price of Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 3-AcetylaminophthalicAnhydride
  • 10g
  • $ 1190.00
  • TCI Chemical
  • 3-Acetamidophthalic Anhydride >98.0%(GC)(T)
  • 5g
  • $ 48.00
  • TCI Chemical
  • 3-Acetamidophthalic Anhydride >98.0%(GC)(T)
  • 1g
  • $ 38.00
  • Labseeker
  • N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)acetamide 97
  • 50g
  • $ 433.00
  • Crysdot
  • N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide 95+%
  • 25g
  • $ 248.00
  • ChemScene
  • 3-Acetamidophthalic Anhydride 99.94%
  • 100g
  • $ 157.00
  • ChemScene
  • 3-Acetamidophthalic Anhydride 99.94%
  • 25g
  • $ 61.00
  • Chemenu
  • N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide 98%
  • 1000g
  • $ 864.00
  • BLDpharm
  • N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide 97%
  • 500g
  • $ 553.00
  • BLDpharm
  • N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide 97%
  • 100g
  • $ 159.00
Total 144 raw suppliers
Chemical Property of Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)- Edit
Chemical Property:
  • Vapor Pressure:1.03E-09mmHg at 25°C 
  • Melting Point:185-186℃ 
  • Refractive Index:1.657 
  • Boiling Point:489.1 °C at 760 mmHg 
  • PKA:13.81±0.20(Predicted) 
  • Flash Point:249.6 °C 
  • PSA:72.47000 
  • Density:1.512 g/cm3 
  • LogP:1.02860 
  • Storage Temp.:Inert atmosphere,Room Temperature 
  • Solubility.:Chloroform (Slightly, Sonicated), Ethyl Acetate (Slightly, Sonicated), Methanol 
Purity/Quality:

99.0% *data from raw suppliers

3-AcetylaminophthalicAnhydride *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses 3-Acetylaminophthalic Anhydride is used in the synthesis of Apremilast, a potent phosphodiesterase 4 and tumor necrosis Factor-α inhibitor used in the treatment of psoriatic arthritis. Also a reagent in the preparation of Tillivalline. Apremilast Impurity 2
Technology Process of Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)-

There total 11 articles about Acetamide,N-(1,3-dihydro-1,3-dioxo-4-isobenzofuranyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
In Isopropyl acetate; at 75 - 95 ℃; Temperature; Large scale;
Guidance literature:
With palladium 10% on activated carbon; hydrogen; at 80 - 115 ℃; under 7500.75 Torr; Temperature; Autoclave;
Guidance literature:
for 4h; Concentration; Temperature; Reflux;
Refernces Edit
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