13-Hydroxytetradecanoic acid

Base Information

• Chemical Name: 13-Hydroxytetradecanoic acid
• CAS No.: 17278-73-8
• Molecular Formula: C14H28O3
• Molecular Weight: 244.37000
• Hs Code.: 2918199090
• DSSTox Substance ID: DTXSID30938206
• Nikkaji Number: J127.390F
• Wikidata: Q27225587
• Mol file: 17278-73-8.mol

Synonyms:13-hydroxytetradecanoic acid;13-Hydroxymyristic acid;17278-73-8;13-hydroxy myristic acid;SCHEMBL1882546;DTXSID30938206;CHEBI:132473;KNFJWKJXKURGQU-UHFFFAOYSA-N;13-HYDROXY-TETRADECANOIC ACID;NS00116615;F73812;Q27225587

Chemical Property of 13-Hydroxytetradecanoic acid

Chemical Property:

• PSA: 57.53000
• LogP: 3.74290
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 12
• Exact Mass: 244.20384475
• Heavy Atom Count: 17
• Complexity: 180

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CCCCCCCCCCCC(=O)O)O

Technology Process of 13-Hydroxytetradecanoic acid

There total 12 articles about 13-Hydroxytetradecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

ethanol (64-17-5) + 11-dodecenoic acid (65423-25-8) → 13-Hydroxymyristic acid (17278-73-8)

Guidance literature:

With potassium fluoride; tert-butyl peroxyacetate; for 18h; regioselective reaction; Sealed tube; Heating; Green chemistry;

DOI:10.1039/c7gc02540h

Reference yield: 51.0%

→ 13-Hydroxymyristic acid (17278-73-8)

Guidance literature:

With nickel(II) iodide; manganese; 2,9-dihexyl-4,7-diphenyl-1,10-phenanthroline;

Reference yield: 46.0%

n-tetradecanoic acid (544-63-8) → 13-Hydroxymyristic acid (17278-73-8)

Guidance literature:

With cytochrome P₄₅₀ BM₃; Enzymatic reaction;

DOI:10.1002/chem.201302402

upstream raw materials:

13-ketotetradecanoic acid methyl ester

sodium myristoate

n-tetradecanoic acid

11-bromo-undecanoic acid methyl ester

Refernces

• 1、 Thesseling, Florian A.,Hutter, Michael C.,Wiek, Constanze,Kowalski, John P.,Rettie, Allan E.,Girhard, Marco. "Novel insights into oxidation of fatty acids and fatty alcohols by cytochrome P450 monooxygenase CYP4B1". . . Retrieved 2019/12/12.
• 2、 -. "CATALYTIC CARBOXYLATION OF ACTIVATED ALKANES AND/OR OLEFINS". Page/Page column 65; 66; 67. . Retrieved 2018/02/28.