2-chloro-10-(4-chlorophenyl)-10-hydroxyanthracen-9(10H)-one

Base Information

• Chemical Name: 2-chloro-10-(4-chlorophenyl)-10-hydroxyanthracen-9(10H)-one
• CAS No.: 6636-08-4
• Molecular Formula: C₂₀H₁₂Cl₂O₂
• Molecular Weight: 355.22
• Mol file: 6636-08-4.mol

Synonyms:Anthrone, 2-chloro-10-(p-chlorophenyl)-10-hydroxy-(8CI); NSC 16428

Chemical Property of 2-chloro-10-(4-chlorophenyl)-10-hydroxyanthracen-9(10H)-one

Chemical Property:

• Vapor Pressure: 6.33E-12mmHg at 25°C
• Boiling Point: 526.8°Cat760mmHg
• Flash Point: 272.4°C
• Density: 1.443g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloro-10-(4-chlorophenyl)-10-hydroxyanthracen-9(10H)-one

There total 3 articles about 2-chloro-10-(4-chlorophenyl)-10-hydroxyanthracen-9(10H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-10-(4-chloro-phenyl)-anthrone (860235-78-5) → 2-chloro-10-(4-chloro-phenyl)-10-hydroxy-anthrone (6636-08-4)

Guidance literature:

With sodium dichromate; water; acetic acid;

DOI:10.1021/ja01293a023

Reference yield:

3,3-bis(4-chlorophenyl)-3H-isobenzofuran-1-one (5449-79-6) → 2-chloro-10-(4-chloro-phenyl)-10-hydroxy-anthrone (6636-08-4)

Guidance literature:

Multi-step reaction with 3 steps

1: zinc-powder; aq.-ethanolic NaOH-solution

2: concentrated sulfuric acid

3: acetic acid; Na₂Cr₂O₇; water

With sodium hydroxide; sodium dichromate; sulfuric acid; water; acetic acid; zinc;

DOI:10.1021/ja01293a023

Reference yield:

2-(4,4'-dichloro-benzhydryl)-benzoic acid → 2-chloro-10-(4-chloro-phenyl)-10-hydroxy-anthrone (6636-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid

2: acetic acid; Na₂Cr₂O₇; water

With sodium dichromate; sulfuric acid; water; acetic acid;

DOI:10.1021/ja01293a023

upstream raw materials:

2-chloro-10-(4-chloro-phenyl)-anthrone

3,3-bis(4-chlorophenyl)-3H-isobenzofuran-1-one