5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER

Base Information

• Chemical Name: 5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER
• CAS No.: 39630-68-7
• Molecular Formula: C12H14 O5
• Molecular Weight: 238.24
• Hs Code.: 2918199090
• Mol file: 39630-68-7.mol

Synonyms:1,3-Benzenedicarboxylicacid, 5-hydroxy-, diethyl ester (9CI); 3,5-Di(carbethoxy)phenol; 5-Hydroxyisophthalicacid diethyl ester; Diethyl 5-hydroxy-1,3-benzenedicarboxylate; Diethyl5-hydroxyisophthalate; Ethyl 5-hydroxyisophthalate

Chemical Property of 5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER

Chemical Property:

• Vapor Pressure: 2.11E-06mmHg at 25°C
• Boiling Point: 382.7°C at 760 mmHg
• Flash Point: 145.3°C
• PSA: 72.83000
• Density: 1.211g/cm³
• LogP: 1.74560
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER

There total 4 articles about 5-HYDROXY-ISOPHTHALIC ACID DIETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethanol (64-17-5) + 5-Hydroxyisophthalic acid (618-83-7) → diethyl 5-hydroxyisophthalate (39630-68-7)

Guidance literature:

With toluene-4-sulfonic acid; for 48h; Reflux;

DOI:10.1016/j.polymer.2016.06.066

Reference yield:

isophthalic acid (121-91-5) → diethyl 5-hydroxyisophthalate (39630-68-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sulfuric acid; N-Bromosuccinimide / 6 h / 60 °C

2: sodium hydroxide; copper(I) oxide / water / 20 h / 130 °C

3: sulfuric acid / 36 h / Reflux

With copper(I) oxide; N-Bromosuccinimide; sulfuric acid; sodium hydroxide; In water;

Reference yield:

5-bromoisophthalic acid (23351-91-9) → diethyl 5-hydroxyisophthalate (39630-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; copper(I) oxide / water / 20 h / 130 °C

2: sulfuric acid / 36 h / Reflux

With copper(I) oxide; sulfuric acid; sodium hydroxide; In water;

upstream raw materials:

ethanol

5-Hydroxyisophthalic acid

5-sulfoisophthalic acid

isophthalic acid

Downstream raw materials:

C₃₂H₄₂O₁₀

1,3-Bis(3,5-dicarbethoxyphenoxy)propane

α,α'-bis<3,5-bis(dicarbethoxy)phenoxy>-o-xylene

Diethyl 5-(4-nitrophenylmethyloxy)isophthalate

Refernces

• 1、 -. "Nano composite of polynucleotide and gold nano rod, and preparation method and applications thereof". Paragraph 0029; 0030; 0031. . Retrieved 2017/08/31.
• 2、 Oguri, Takahiro,Kawahara, Akie,Kihara, Nobuhiro. "Epoxy resin bearing diacylhydrazine moiety as a degradable adhesive for traceless oxidative removal". . p. 83 - 89. Retrieved 2016/07/19.