Benzenecarbothioic acid, S-2-benzoxazolyl ester

Base Information

• Chemical Name: Benzenecarbothioic acid, S-2-benzoxazolyl ester
• CAS No.: 17688-44-7
• Molecular Formula: C14H9NO2S
• Molecular Weight: 255.297
• Mol file: 17688-44-7.mol

Synonyms:S-(2-Benzoxazolyl) Thiobenzoate;

Chemical Property of Benzenecarbothioic acid, S-2-benzoxazolyl ester

Chemical Property:

• PSA: 68.40000
• LogP: 3.76030

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenecarbothioic acid, S-2-benzoxazolyl ester

There total 2 articles about Benzenecarbothioic acid, S-2-benzoxazolyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzoyl chloride (98-88-4) + 2-sulfanyl-1,3-benzoxazole (2382-96-9,118090-08-7) → S-(benzoxazol-2-yl) thiobenzolate (17688-44-7)

Guidance literature:

With potassium carbonate; 1-butyl-3-methylimidazolium Tetrafluoroborate; at 50 ℃; for 2h;

DOI:10.1081/SCC-120037917

Reference yield: 92.0%

benzo[d]oxazole-2-(3H)-thione (2382-96-9) + benzoyl chloride (98-88-4) → 3-benzoyl-2(3H)-benzoxazolethione (33388-23-7) + S-(benzoxazol-2-yl) thiobenzolate (17688-44-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; benzene; for 3h; Heating;

DOI:10.3987/COM-03-S(P)10

Reference yield: 95.0%

S-(benzoxazol-2-yl) thiobenzolate (17688-44-7) + aniline (62-53-3) → N-phenyl benzoyl amide (93-98-1,5705-51-1)

Guidance literature:

In tetrahydrofuran; at 15 ℃; for 0.166667h;

DOI:10.1055/s-1981-29674

upstream raw materials:

benzoyl chloride

2-sulfanyl-1,3-benzoxazole

benzo[d]oxazole-2-(3H)-thione

Downstream raw materials:

4-nitrobenzyl benzoate

4'-(benzyloxy)benzanilide

p-benzoylaminophenol

2-benzamidoethyl benzoate

Refernces

• 1、 Duarte, Anaí,Cunico, Wilson,Pereira, Claudio M.P.,Flores, Alex F.C.,Freitag, Rogério A.,Siqueira, Geonir M.. "Ultrasound promoted synthesis of thioesters from 2-mercaptobenzoxa(thia)zoles". experimental part. p. 281 - 283. Retrieved 2010/12/25.
• 2、 Nishio, Takehiko,Shiwa, Kiyoko. "Acylation and alkoxycarbonylation of benzoxazoline-2-thione and benzothiazoline-2-thione". . p. 313 - 324. Retrieved 2007/10/03.