N-Ethyl-2,2-dimethyl-1-propanamine hydrochloride

Base Information

• Chemical Name: N-Ethyl-2,2-dimethyl-1-propanamine hydrochloride
• CAS No.: 17839-28-0
• Molecular Formula: C7H17N
• Molecular Weight: 151.67800
• Hs Code.: 2921199090
• European Community (EC) Number: 835-156-6
• DSSTox Substance ID: DTXSID90598805
• Mol file: 17839-28-0.mol

Synonyms:N-ETHYL-2,2-DIMETHYL-1-PROPANAMINE HYDROCHLORIDE;17839-28-0;22675-77-0;N-ethyl-2,2-dimethylpropan-1-amine hydrochloride;(2,2-dimethylpropyl)(ethyl)amine hydrochloride;N-ethyl-2,2-dimethylpropan-1-amine;hydrochloride;SCHEMBL4019292;DTXSID90598805;RZUZRKJVXPJKJE-UHFFFAOYSA-N;MFCD11226476;AKOS005110939;N-Ethyl-2,2-dimethyl-1-propanamine HCl;(2,2-Dimethylpropyl)ethylamine hydrochloride;CS-0298656;EN300-216186;(2,2-dimethylpropyl)ethylamine(SALTDATA: HCl);N-Ethyl-2,2-dimethylpropan-1-amine--hydrogen chloride (1/1)

Chemical Property of N-Ethyl-2,2-dimethyl-1-propanamine hydrochloride

Chemical Property:

• PSA: 12.03000
• LogP: 2.83490
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 151.1127773
• Heavy Atom Count: 9
• Complexity: 51.9

Purity/Quality:

98%min ^*data from raw suppliers

(2,2-dimethylpropyl)ethylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCNCC(C)(C)C.Cl

Technology Process of N-Ethyl-2,2-dimethyl-1-propanamine hydrochloride

There total 6 articles about N-Ethyl-2,2-dimethyl-1-propanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2.2-dimethylpropylamine (5813-64-9) + 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran (96042-30-7) + acetyl chloride (75-36-5) → N-neopentyl-acetamide (15501-39-0) + N-ethylneopentylamine (17839-28-0)

Guidance literature:

With triethylamine;

Reference yield: 87.0%

ethylamine (75-04-7,85404-22-4) + pivalaldehyde (630-19-3) → N-ethylneopentylamine (17839-28-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 2h; Heating;

DOI:10.1039/b616606g

Reference yield:

2,2-Dimethyl-3-pentanonoxim (73153-82-9) → 1-Ethyl-2,2-dimethylpropylamin (73153-81-8) + N-ethylneopentylamine (17839-28-0)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 20h; Yield given. Yields of byproduct given; Heating;

upstream raw materials:

tert-butyl isocyanide

triethyloxonium fluoroborate

2,2-Dimethyl-3-pentanonoxim

2.2-dimethylpropylamine

Refernces

• 1、 -. "N-heterocyclic inhibitors of TNF-α expression". . . Retrieved 2008/06/13.
• 2、 -. "N- heterocyclic inhibitors of TNF-alpha expression". . . Retrieved 2008/06/13.