Benzenamine, 2-chloro-4-ethoxy-

Base Information Edit

Chemical Name:Benzenamine, 2-chloro-4-ethoxy-
CAS No.:178452-11-4
Molecular Formula:C8H10ClNO
Molecular Weight:171.626
Hs Code.:
DSSTox Substance ID:DTXSID20440661
Mol file:178452-11-4.mol

Synonyms:2-chloro-4-ethoxyaniline;Benzenamine, 2-chloro-4-ethoxy-;178452-11-4;2-chloro-4-ethoxybenzenaMine;SCHEMBL1876235;DTXSID20440661;AKOS011392050;BS-53322;Y14111

Suppliers and Price of Benzenamine, 2-chloro-4-ethoxy-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
2-Chloro-4-ethoxyaniline 95%
1g
$ 849.00

Ambeed
2-Chloro-4-ethoxyaniline 95%
250mg
$ 341.00

Ambeed
2-Chloro-4-ethoxyaniline 95%
100mg
$ 227.00

Total 1 raw suppliers

Chemical Property of Benzenamine, 2-chloro-4-ethoxy- Edit

Chemical Property:

Melting Point:99 °C
Boiling Point:264.9±20.0 °C(Predicted)
PKA:3.31±0.10(Predicted)
PSA：35.25000
Density:1.190±0.06 g/cm3(Predicted)
LogP:2.90210
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:171.0450916
Heavy Atom Count:11
Complexity:121

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-4-ethoxyaniline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC1=CC(=C(C=C1)N)Cl

Technology Process of Benzenamine, 2-chloro-4-ethoxy-

There total 8 articles about Benzenamine, 2-chloro-4-ethoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5391-55-9
3-chloro-4-nitro-phenetole

: 178452-11-4
2-chloro-4-ethoxyaniline

Guidance literature:: With hydrogenchloride; iron; In ethanol; for 6h; Yield given; Heating;
DOI:10.1080/00397919608003794

Reference yield:

: 2106-50-5
2-chloro-4-fluoro-1-nitrobenzene

: 178452-11-4
2-chloro-4-ethoxyaniline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 60 °C

2: tin(II) chloride dihdyrate / methanol / 12 h / 20 °C

With tin(II) chloride dihdyrate; sodium hydride; In methanol; N,N-dimethyl-formamide;
DOI:10.1038/s41401-020-00552-w

Reference yield:

: 108-43-0
3-monochlorophenol

: 178452-11-4
2-chloro-4-ethoxyaniline

Guidance literature:: Multi-step reaction with 3 steps

1: 20 percent / NaNO₃, H₂SO₄ / H₂O / 4 h / 25 °C

2: NaOEt / ethanol / 10 h / Heating

3: Fe, conc.HCl / ethanol / 6 h / Heating

With hydrogenchloride; sodium nitrate; sulfuric acid; sodium ethanolate; iron; In ethanol; water;
DOI:10.1080/00397919608003794