Silacyclopentane, 1-phenyl-

Base Information

• Chemical Name: Silacyclopentane, 1-phenyl-
• CAS No.: 17903-30-9
• Molecular Formula: C10H14Si
• Molecular Weight: 162.307
• Mol file: 17903-30-9.mol

Synonyms:

Chemical Property of Silacyclopentane, 1-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Silacyclopentane, 1-phenyl-

There total 7 articles about Silacyclopentane, 1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

1-chloro-1-phenylsilacyclopentane (7488-24-6) → 1-phenylsilacyclopentane (17903-30-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

Reference yield: 17.0%

1,4-dibromo-butane (110-52-1) + Phenyltrichlorosilane (98-13-5) → 1-phenylsilacyclopentane (17903-30-9)

Guidance literature:

1,4-dibromo-butane; Phenyltrichlorosilane; With magnesium; In tetrahydrofuran; ethylene dibromide; for 18h; Inert atmosphere; Reflux;

With lithium aluminium tetrahydride; In tetrahydrofuran; ethylene dibromide; at 0 ℃; for 12h; Inert atmosphere; Reflux;

DOI:10.1002/anie.201813229

Reference yield:

phenylsilane (694-53-1) + methylene cyclopropane (6142-73-0) → C10H14Si + 1-phenylsilacyclopentane (17903-30-9)

Guidance literature:

With (DIPPnacnac)MgH; In benzene-d6; at -35 - 80 ℃; for 18h; Temperature; Glovebox; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1021/jacs.0c03383

upstream raw materials:

1-chloro-1-phenylsilacyclopentane

Phenyltrichlorosilane

1,4-dibromo-butane

phenylsilane

Downstream raw materials:

(S)-2-phenyloct-3-yn-2-ol

Refernces

• 1、 Seliger, Jan,Dong, Xichang,Oestreich, Martin. "Kinetic Resolution of Tertiary Propargylic Alcohols by Enantioselective Cu?H-Catalyzed Si?O Coupling". supporting information. p. 1970 - 1974. Retrieved 2019/01/29.