cis-4-methylcyclohexanecarboxylic acid

Base Information

• Chemical Name: cis-4-methylcyclohexanecarboxylic acid
• CAS No.: 934-67-8
• Molecular Formula: C8H14 O2
• Molecular Weight: 142.198
• Hs Code.: 2916209090
• Mol file: 934-67-8.mol

Synonyms:cis-4-Methylcyclohexanecarboxylicacid

Chemical Property of cis-4-methylcyclohexanecarboxylic acid

Chemical Property:

• Vapor Pressure: 0.008mmHg at 25°C
• Melting Point: 28.0-29.5 °C
• Boiling Point: 247.5°Cat760mmHg
• Flash Point: 110.7°C
• PSA: 37.30000
• Density: 1.025g/cm³
• LogP: 1.89730

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-4-methylcyclohexanecarboxylicacid 0.87 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of cis-4-methylcyclohexanecarboxylic acid

There total 29 articles about cis-4-methylcyclohexanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.2%

→ 4-methylcyclohexanecarboxylic acid (4331-54-8) + trans-4-methylcyclohexanecarboxylic acid (934-67-8,4331-54-8,13064-83-0)

Guidance literature:

Reference yield: 90.0%

p-Toluic acid (99-94-5) → trans-4-methylcyclohexanecarboxylic acid (934-67-8,4331-54-8,13064-83-0) + (cis)-4-methylcyclohexanecarboxylic acid (934-67-8)

Guidance literature:

p-Toluic acid; With sodium hydroxide; hydrogen; In water; at 140 - 150 ℃; for 1h; under 22502.3 - 30003 Torr;

With sodium hydroxide; In water; at 260 - 280 ℃; for 2h; under 22502.3 - 30003 Torr; Further stages.;

DOI:10.1016/j.tetlet.2004.06.117

Reference yield: 90.0%

p-Toluic acid (99-94-5) → trans-4-methylcyclohexanecarboxylic acid (934-67-8,4331-54-8,13064-83-0) + (cis)-4-methylcyclohexanecarboxylic acid (934-67-8)

Guidance literature:

p-Toluic acid; With sodium hydroxide; hydrogen; In water; at 140 - 150 ℃; for 1h; under 22502.3 - 30003 Torr;

With sodium hydroxide; In water; at 260 - 280 ℃; for 2h; under 22502.3 - 30003 Torr; Further stages.;

DOI:10.1016/j.tetlet.2004.06.117

upstream raw materials:

4-acetyl-1-methylcyclohexane

p-Toluic acid

p-methylcyclohexanol

carbon dioxide

Downstream raw materials:

trans-4-methyl-1-(ethoxycarbonyl)cyclohexane

(trans)-4-methylcyclohexane-1-carboxamide

trans-4-methyl-cyclohexane-carboxylic acid-⁽¹⁾-(4-bromo-phenacyl ester)

4-methyl-1-cyclohexanecarboxylic acid methyl ester

Refernces

• 1、 Jiang, Hezhan,Yu, Xiaolong,Nie, Renfeng,Lu, Xinhuan,Zhou, Dan,Xia, Qinghua. "Selective hydrogenation of aromatic carboxylic acids over basic N-doped mesoporous carbon supported palladium catalysts". . p. 73 - 81. Retrieved 2016/05/02.
• 2、 Bazurin, Alexey A.,Krasnikov, Sergey V.,Obuchova, Tatiana A.,Danilova, Angelina S.,Balakin, Konstantin V.. "Improved synthesis of trans-4-alkylcyclohexane carboxylic acids". . p. 6669 - 6672. Retrieved 2007/10/03.