3,5-Dibromobenzyl bromide

Base Information

• Chemical Name: 3,5-Dibromobenzyl bromide
• CAS No.: 56908-88-4
• Molecular Formula: C7H5Br3
• Molecular Weight: 328.829
• Hs Code.: 29039990
• Mol file: 56908-88-4.mol

Synonyms:3,5-Dibromo?benzyl?bromide;1,3-dibromo-5-(bromomethyl)benzene;

Chemical Property of 3,5-Dibromobenzyl bromide

Chemical Property:

• Appearance/Colour: white to beige-brownish powder
• Vapor Pressure: 0.00076mmHg at 25°C
• Melting Point: 93-97 °C
• Refractive Index: 1.636
• Boiling Point: 316.5 °C at 760 mmHg
• Flash Point: 142.2 °C
• PSA: 0.00000
• Density: 2.173 g/cm³
• LogP: 4.10650
• Storage Temp.: Flammables area
• Solubility.: Soluble in toluene

Purity/Quality:

99% ^*data from raw suppliers

3,5-Dibromobenzyl Bromide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,C
• Hazard Codes: C-F,C,F
• Statements: 34-11
• Safety Statements: 45-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3,5-Dibromobenzyl bromide, is an important raw material and intermediateintermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of 3,5-Dibromobenzyl bromide

There total 4 articles about 3,5-Dibromobenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3,5-dibromophenyl)methanol (145691-59-4) → 3,5-dibromobenzyl bromide (56908-88-4)

Guidance literature:

With carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1002/chem.201102260

Reference yield: 92.0%

3,5-dibromobenzaldehyde (56990-02-4) → 3,5-dibromobenzyl bromide (56908-88-4)

Guidance literature:

With boron tribromide; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1080/10610278.2010.550290

Reference yield: 74.0%

3,5-dibromotoluene (1611-92-3) → 3,5-dibromobenzyl bromide (56908-88-4)

Guidance literature:

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; for 24h; Reflux;

upstream raw materials:

3,5-dibromotoluene

(3,5-dibromophenyl)methanol

3,5-dibromobenzaldehyde

Downstream raw materials:

(3,5-dibromophenyl)methanol

N-(3,5-dibromobenzyl)coumarin 2

ethyl 1-[(3,5-dibromophenyl)methyl]-3-[4-(1,1-dimethylethyl)phenyl]-1H-indole-2-carboxylate

Refernces

• 1、 Liu, Simin,Whisenhunt-Ioup, Sarah E.,Gibb, Corinne L. D.,Gibb, Bruce C.. "An improved synthesis of 'octa-acid' deep-cavity cavitand". . p. 480 - 485. Retrieved 2011.
• 2、 Hussein, Mohanad A.,Nguyen, Thanh Vinh. "Promotion of Appel-type reactions by N-heterocyclic carbenes". supporting information. p. 7962 - 7965. Retrieved 2019/07/12.