3-Methyl-4-nitrobenzamide

Base Information

• Chemical Name: 3-Methyl-4-nitrobenzamide
• CAS No.: 99584-85-7
• Molecular Formula: C8H8N2O3
• Molecular Weight: 180.163
• Hs Code.: 2924299090
• Mol file: 99584-85-7.mol

Synonyms:3-methyl-4-nitrobenzamide;

Chemical Property of 3-Methyl-4-nitrobenzamide

Chemical Property:

• Vapor Pressure: 0.000316mmHg at 25°C
• Melting Point: 158-160 °C
• Refractive Index: 1.599
• Boiling Point: 320.5 °C at 760 mmHg
• PKA: 15.14±0.50(Predicted)
• Flash Point: 147.6 °C
• PSA: 88.91000
• Density: 1.322 g/cm³
• LogP: 2.22560
• Storage Temp.: 2-8°C
• Water Solubility.: Soluble in alcohol, slightly soluble in hot water.

Purity/Quality:

99%, ^*data from raw suppliers

3-Methyl-4-Nitrobenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R22:Harmful if swallowed.
• Hazard Codes: R22:Harmful if swallowed.
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: 3-Methyl-4-nitrobenzamide is used as synthetic organic intermediates.

Technology Process of 3-Methyl-4-nitrobenzamide

There total 4 articles about 3-Methyl-4-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-methyl-4-nitrobenzonitrile (96784-54-2) → 3-methyl-4-nitro benzamide (99584-85-7)

Guidance literature:

With manganese(IV) oxide; water; In isopropyl alcohol; at 100 ℃; for 0.333333h; under 5171.62 Torr;

DOI:10.1021/ol403591c

Reference yield:

3-methyl-4-nitro-benzoyl chloride (35675-46-8) → 3-methyl-4-nitro benzamide (99584-85-7)

Guidance literature:

With ammonia; In 1,2-dimethoxyethane; water; at 10 - 15 ℃;

Reference yield:

3-methyl-4-nitrobenzoic acid (3113-71-1) → 3-methyl-4-nitro benzamide (99584-85-7)

Guidance literature:

With phosphorus pentachloride; Behandlung des entstandenen Chlorids mit konz. Ammoniak;

upstream raw materials:

3-methyl-4-nitrobenzoic acid

3-methyl-4-nitro-benzoyl chloride

3-methyl-4-nitrobenzonitrile

Downstream raw materials:

1-(3-methyl-4-nitrobenzyl)methanamine

Refernces

• 1、 -. "DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS". Page/Page column 88. . Retrieved 2014/11/13.
• 2、 -. "PHARMACEUTICALS, COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME". Page/Page column 26-27. . Retrieved 2008/12/07.